CAS 2425563-60-4

Formula: C22H27N3O2S

InChI: InChI=1S/C22H27N3O2S/c1-14-9-11-25(15(2)12-14)22(27)19-17-7-3-4-8-18(17)28-21(19)24-20(26)16-6-5-10-23-13-16/h5-6,10,13-15H,3-4,7-9,11-12H2,1-2H3,(H,24,26)/t14-,15-/m1/s1

InChI key: PCTBZMHJFHFNAH-HUUCEWRRSA-N

SMILES: C[C@@H]1CCN([C@@H](C1)C)C(=O)C2=C(SC3=C2CCCC3)NC(=O)C4=CN=CC=C4

TF-S14

CAS: 2425563-60-4

TF-S14 is an inverse agonist of RORγt. It functions by binding to RORγt and inhibiting its activity, leading to a reduction in Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22. TF-S14 is applicable in research related to autoimmune diseases and allogeneic transplant rejection.

Formula: C₂₂H₂₇N₃O₂S

Color and Shape: Solid

Molecular weight: 397.53

Ref: TM-T88018