CAS 2434-53-9

6-Amino-1-methyluracil

Description:

6-Amino-1-methyluracil is a pyrimidine derivative characterized by the presence of an amino group at the 6-position and a methyl group at the 1-position of the uracil structure. This compound is a white to off-white solid that is soluble in water and exhibits moderate stability under standard conditions. It is primarily of interest in biochemical research due to its potential role as a nucleobase analog and its implications in nucleic acid metabolism. The amino group can participate in hydrogen bonding, influencing its interactions with other biomolecules. Additionally, 6-Amino-1-methyluracil can undergo various chemical reactions typical of pyrimidine derivatives, including methylation and acylation. Its structural modifications can lead to variations in biological activity, making it a subject of study in medicinal chemistry and pharmacology. Overall, this compound serves as a valuable tool in understanding nucleic acid function and the development of therapeutic agents targeting nucleic acid processes.

Formula: C₅H₇N₃O₂

InChI: InChI=1S/C5H7N3O2/c1-8-3(6)2-4(9)7-5(8)10/h2H,6H2,1H3,(H,7,9,10)

InChI key: InChIKey=GZLZRPNUDBIQBM-UHFFFAOYSA-N

SMILES: CN1C(N)=CC(=O)NC1=O

Synonyms:

• 1-Methyl-6-aminouracil
• 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-methyl-
• 6-Amino-1-Methyl Uracil
• 6-Amino-1-methyl-1H-pyrimidine-2,4-dione
• 6-Amino-1-methyl-2,4(1H,3H)-pyrimidinedione
• 6-amino-1-methylpyrimidine-2,4(1H,3H)-dione
• NSC 7369
• Uracil, 6-amino-1-methyl-
• 6-Amino-1-methyluracil

6-Amino-1-methyluracil

CAS: 2434-53-9

Formula: C₅H₇N₃O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 141.13

Ref: 3B-A2449

6-Amino-1-methyluracil

CAS: 2434-53-9

Formula: C₅H₇N₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 141.1280

Ref: IN-DA003N25

6-Amino-1-methyluracil

CAS: 2434-53-9

Formula: C₅H₇N₃O₂

Molecular weight: 141.13

Ref: 7W-GN7099

6-Amino-1-Methyluracil

CAS: 2434-53-9

6-Amino-1-Methyluracil

Formula: C₅H₇N₃O₂

Purity: 99%

Molecular weight: 141.13

Ref: 54-OR1011977

6-Amino-1-methyluracil

CAS: 2434-53-9

Formula: C₅H₇N₃O₂

Molecular weight: 141.13

Ref: 4Z-U-0517

6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione

CAS: 2434-53-9

Formula: C₅H₇N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 141.13

Ref: 10-F218873

6-Amino-1-methyluracil

Controlled Product

CAS: 2434-53-9

Applications 6-Amino-1-methyluracil is known to exert inhibitory effects towards DNA repair glycosylase. It is also known to be used as a flame retardant.
References Speina, E., et al.: Acta. Bioch. Polonica., 52, 167 (2005);

Formula: C₅H₇N₃O₂

Color and Shape: Neat

Molecular weight: 141.13

Ref: TR-A616935

6-Amino-1-methyluracil

CAS: 2434-53-9

6-Amino-1-methyluracil is a synthetic drug that is used in the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. It is also used to treat cancer, such as leukemia and in the treatment of bacterial infections. 6-Amino-1-methyluracil inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase. This inhibition prevents DNA replication and transcription, which leads to cell death. 6-Amino-1-methyluracil binds to cellular proteins through its amino group and hydroxyl group, which are not involved in its chemical reactions. 6-Amino-1-methyluracil has shown great promise as a template molecule for the synthesis of new drugs.

Purity: Min. 95%

Ref: 3D-NA03107