CAS 244767-67-7

4-[4-(2,4,6-Trimethylphenylamino)pyrimidin-2-ylamino]benzonitrile

Description:

4-[4-(2,4,6-Trimethylphenylamino)pyrimidin-2-ylamino]benzonitrile, with the CAS number 244767-67-7, is a chemical compound characterized by its complex structure, which includes a pyrimidine ring and a benzonitrile moiety. This compound features multiple aromatic systems, contributing to its potential as a ligand in coordination chemistry or as a building block in organic synthesis. The presence of the trimethylphenylamino group enhances its solubility and may influence its electronic properties, making it suitable for applications in pharmaceuticals or materials science. The compound's molecular structure suggests it may exhibit interesting biological activity, potentially acting as an inhibitor or modulator in various biochemical pathways. Additionally, its stability and reactivity can be influenced by the functional groups present, which may affect its interactions in different environments. Overall, this compound represents a class of organic molecules that can be explored for diverse applications in research and industry.

Formula: C₂₀H₁₉N₅

InChI: InChI=1/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25)

InChI key: ILAYIAGXTHKHNT-UHFFFAOYSA-N

SMILES: Cc1cc(C)c(c(C)c1)N=c1ccnc(Nc2ccc(cc2)C#N)[nH]1

Synonyms:

• Dapivirine
• Tmc-120
• R-147681
• 4-({4-[(2,4,6-Trimethylphenyl)Amino]Pyrimidin-2-Yl}Amino)Benzonitrile
• Dapivirine,TMC-120
• DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE
• Dapivirine 4-[[4-[(2,4,6-Trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile
• TMC 120R147681
• TMC 120R147681 Dapivirine
• 4-(4-(MESITYLAMINO)PYRIMIDIN-2-YLAMINO)BENZONITRILE
• CS-566
• DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE USP/EP/BP
• Benzonitrile, 4-[[4-[(2,4,6-triMethylphenyl)aMino]-2-pyriMidinyl]aMino]-
• R 147681; TMC 120; TMC 120; R147681
• Dapivirine, >=98%
• 4-[[4-[(2,4,6-TriMethylphenyl)aMino]-2-pyriMidinyl]aMino]benzonitrile
• Dapivirine,TMC-120, 244767-67-7
• DAPIVIRINE(TMC 120, TMC 120 R147681)
• Dapivirine TMC120, AIDS-105293
• Dapivirine - R 147681 | TMC 120

Dapivirine

CAS: 244767-67-7

Formula: C₂₀H₁₉N₅

Purity: >97.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 329.41

Ref: 3B-D6168

Dapivirine

CAS: 244767-67-7

Dapivirine

Formula: C₂₀H₁₉N₅

Purity: 99%

Molecular weight: 329.4

Ref: 54-BUP11411

4-[[4-(2,4,6-Trimethylanilino)Pyrimidin-2-Yl]Amino]Benzonitrile

CAS: 244767-67-7

4-[[4-(2,4,6-Trimethylanilino)Pyrimidin-2-Yl]Amino]Benzonitrile

Formula: C₂₀H₁₉N₅

Purity: 98%

Molecular weight: 329.4

Ref: 54-OR1027278

Benzonitrile, 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-

CAS: 244767-67-7

Formula: C₂₀H₁₉N₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 329.3984

Ref: IN-DA002O9Y

Dapivirine

Controlled Product

CAS: 244767-67-7

Applications Non-nucleoside Reverse Transcriptase inhibitor. An antiviral agent.
References Qin, B., et al.: J. Med. Chem., 53, 4906 (2010), Woolfson, A., et al.: Int. J. Pharm., 388, 136 (2010), Johnson, T., et al.: Eur. J. Pharm. Sci., 39, 203 (2010),

Formula: C₂₀H₁₉N₅

Color and Shape: Neat

Molecular weight: 329.4

Ref: TR-D185500

Dapivirine

CAS: 244767-67-7

Formula: C₂₀H₁₉N₅

Molecular weight: 329.41

Ref: 4Z-D-281001

Dapivirine

CAS: 244767-67-7

Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.

Formula: C₂₀H₁₉N₅

Purity: 98% - 99.77%

Color and Shape: Solid

Molecular weight: 329.4

Ref: TM-T1815

Dapivirine

CAS: 244767-67-7

4-((4-(Mesitylamino)pyrimidin-2-yl)amino)benzonitrile

Formula: C₂₀H₁₉N₅

Purity: 98%

Molecular weight: 329.4

Ref: IN-DG123450

Dapivirine

CAS: 244767-67-7

Dapivirine is a non-nucleoside reverse transcriptase inhibitor with action on HIV-1 reverse transcriptase and is used for preventing HIV infection through vaginal rings.

Formula: C₂₀H₁₉N₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 329.4 g/mol

Ref: 3D-FD20796

DAPIVIRINE,TMC-120

CAS: 244767-67-7

Formula: C₂₀H₁₉N₅

Purity: 98%

Color and Shape: Liquid

Molecular weight: 329.407

Ref: 10-F468331

Dapivirine

CAS: 244767-67-7

Formula: C₂₀H₁₉N₅

Molecular weight: 329.41

Ref: ST-EA-CP-D211000