CAS 24527-27-3

Spiclomazine

Description:

Spiclomazine, with the CAS number 24527-27-3, is a chemical compound that belongs to the class of phenothiazine derivatives. It is primarily recognized for its use as an antipsychotic and antiemetic agent. The compound exhibits a range of pharmacological properties, including dopamine receptor antagonism, which contributes to its therapeutic effects in managing psychiatric disorders and preventing nausea and vomiting. Spiclomazine is characterized by its ability to cross the blood-brain barrier, making it effective in central nervous system applications. Additionally, it may possess sedative properties, which can be beneficial in certain clinical contexts. The compound's safety profile, potential side effects, and interactions with other medications are important considerations in its use. As with many pharmaceuticals, the specific characteristics, including solubility, stability, and metabolic pathways, can influence its efficacy and application in medical settings. Overall, Spiclomazine represents a significant compound within the realm of psychopharmacology.

Formula: C₂₂H₂₄ClN₃OS₂

InChI: InChI=1S/C22H24ClN3OS2/c23-16-6-7-20-18(14-16)26(17-4-1-2-5-19(17)29-20)11-3-10-25-12-8-22(9-13-25)24-21(27)15-28-22/h1-2,4-7,14H,3,8-13,15H2,(H,24,27)

InChI key: InChIKey=CFOYBMUYCBSDAL-UHFFFAOYSA-N

SMILES: C(CCN1CCC2(CC1)NC(=O)CS2)N3C=4C(SC=5C3=CC=CC5)=CC=C(Cl)C4

Synonyms:

• 1-Thia-4,8-diazaspiro[4.5]decan-3-one, 8-[3-(2-chlorophenothiazin-10-yl)propyl]-
• 1-thia-4,8-diazaspiro[4.5]decan-3-one, 8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-
• 24527-27-3
• 8-[3-(2-Chloro-10-phenothiazinyl)propyl]-3-oxo-1-thia-4,8-diazaspiro[4.5]decane
• 8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one
• Clospirazine
• Diceplon
• Disepron
• Spiclomazine

Spiclomazine

CAS: 24527-27-3

Spiclomazine

Formula: C₂₂H₂₄ClN₃OS₂

Purity: 99%

Molecular weight: 446.03

Ref: 54-OR1103617

Spiclomazine

CAS: 24527-27-3

Formula: C₂₂H₂₄ClN₃OS₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 446.0285

Ref: IN-DA00C3EJ

Spiclomazine

Controlled Product

CAS: 24527-27-3

Applications Spiclomazine is a phenothiazine derivative that inhibits human platelet type B monoaine oxidase(MAO).
References Suzuki, O., et. al.: Life Sci., 42, 2131 (1988)

Formula: C₂₂H₂₄ClN₃OS₂

Color and Shape: Neat

Molecular weight: 446.03

Ref: TR-S681760

Spiclomazine-d6

Controlled Product

CAS: 24527-27-3

Formula: C₂₂D₆H₁₈ClN₃OS₂

Color and Shape: Neat

Molecular weight: 452.065

Ref: TR-S681762

Spiclomazine free base

CAS: 24527-27-3

Spiclomazine free base is an antipsychotic compound.

Formula: C₂₂H₂₄ClN₃OS₂

Molecular weight: 446.03

Ref: TM-T202567