CAS 24666-56-6

3-Amino-2,6-piperidinedione hydrochloride

Description:

3-Amino-2,6-piperidinedione hydrochloride, with the CAS number 24666-56-6, is a chemical compound characterized by its piperidine ring structure, which includes two carbonyl groups and an amino group. This compound typically appears as a white to off-white crystalline solid and is soluble in water, which is a common trait for many hydrochloride salts. The presence of the amino group contributes to its basicity, while the carbonyl groups can participate in various chemical reactions, such as nucleophilic attacks. It is often used in pharmaceutical research and development due to its potential biological activity, particularly in the synthesis of various medicinal compounds. The hydrochloride form enhances its stability and solubility, making it easier to handle in laboratory settings. As with many chemical substances, proper safety precautions should be taken when handling this compound, including the use of personal protective equipment to avoid inhalation or skin contact.

Formula: C₅H₈N₂O₂・HCl

InChI: InChI=1/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H

InChI key: YCPULGHBTPQLRH-UHFFFAOYSA-N

SMILES: C1CC(=NC(=O)C1N)O.Cl

Synonyms:

• 2,6-Dioxopiperidine-3-ammonium chloride
• 3-Aminopiperidine-2,6-Dione Hydrochloride (1:1)
• 2,6-Piperidinedione,3-amino-,hydrochloride
• 3-Aminopiperidine-2,6-dione hydrochloride
• 2,6-Piperidinedione, 3-amino-, monohydrochloride, (+-)-
• (+-)-3-Amino-2,6-piperidinedione monohydrochloride
• Glutamic acid imide-DL-hydrochloride
• 3-Amino-2,6-dioxo-piperidine hydrochloride
• 3-Amino Piperdine-2,6-Dion Hydrochloride

3-Amino-2,6-piperidinedione Hydrochloride

CAS: 24666-56-6

Formula: C₅H₈N₂O₂·HCl

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 164.59

Ref: 3B-A2691

Lenalidomide Impurity 6 HCl

CAS: 24666-56-6

Formula: C₅H₈N₂O₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 128.13 36.46

Ref: 4Z-L-269

3-Amino-2,6-piperidinedione Hydrochloride

CAS: 24666-56-6

Formula: C₅H₉ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 164.5902

Ref: IN-DA002OZY

3-Aminopiperidine-2,6-dione hydrochloride

CAS: 24666-56-6

Formula: C₅H₉ClN₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 164.59

Ref: 10-F078697

3-Aminopiperidine-2,6-dione Hydrochloride

Controlled Product

CAS: 24666-56-6

Applications 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.
References Kronke, J., et al.: Nature 523, 183 (2015); Liu C., et al.: Faming Zhuanli Shenqing CN 105348257 A 20160224 (2016); Rao, R., et al. : PCT Int. Appl. WO 2016024286 A2 20160218 (2016)

Formula: C₅H₈N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 164.59

Ref: TR-A632980

3-Aminopiperidine-2,6-dione hydrochloride

CAS: 24666-56-6

3-Aminopiperidine-2,6-dione hydrochloride

Formula: C₅H₈N₂O₂·ClH

Purity: 97%

Color and Shape: Solid

Molecular weight: 164.59015

Ref: 54-OR20048

3-Aminopiperidine-2,6-dione hydrochloride

CAS: 24666-56-6

3-Aminopiperidine-2,6-dione hydrochloride

Formula: C₅H₉ClN₂O₂

Purity: 97%

Molecular weight: 164.59

Ref: IN-DG170886

3-Aminopiperidine-2,6-dione hydrochloride salt

CAS: 24666-56-6

3-Aminopiperidine-2,6-dione hydrochloride salt (3AP) is a synthetic agent that has been shown to inhibit prostate cancer cell growth. 3AP inhibits the synthesis of DNA by inhibiting the enzyme benzoate and potently inhibits the enzyme pomalidomide synthetase. This drug also has antiangiogenic properties and has been shown to reduce expression of TNF-α in human myeloid leukemia cells. 3AP is not active against HL60 cells, which are a type of white blood cell. It can be used as an alternative treatment for cancer in patients who have failed to respond to other therapies or who cannot tolerate them.

Formula: C₅H₈N₂O₂·HCl

Purity: Min 97.0%

Color and Shape: Off-White Slightly Yellow Powder

Molecular weight: 164.59 g/mol

Ref: 3D-FA11978

Lenalidomide Impurity 6

CAS: 24666-56-6

Formula: C₅H₈N₂O₂HCl

Molecular weight: 128.1 : 36.5

Ref: ST-EA-CP-L27006