CAS 247068-85-5

1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1)

Description:

1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1), with CAS number 247068-85-5, is a chemical compound characterized by its complex structure that includes a pentanone backbone, an amino group, and an epoxide moiety. This compound features a trifluoroacetate group, which enhances its reactivity and solubility in various solvents. The presence of the amino group suggests potential for hydrogen bonding and reactivity in nucleophilic substitution reactions. The epoxide ring contributes to its chemical stability while also providing sites for further chemical transformations. The stereochemistry indicated by the (2R) and (2S) designations suggests specific spatial arrangements of atoms, which can influence the compound's biological activity and interactions. Overall, this compound may exhibit unique properties that could be explored in synthetic chemistry, pharmaceuticals, or materials science, depending on its reactivity and functional groups.

Formula: C₉H₁₇NO₂·C₂HF₃O₂

InChI: InChI=1S/C9H17NO2.C2HF3O2/c1-6(2)4-7(10)8(11)9(3)5-12-9;3-2(4,5)1(6)7/h6-7H,4-5,10H2,1-3H3;(H,6,7)/t7-,9+;/m0./s1

InChI key: InChIKey=OWGGQBZQMQMPBI-DKXTVVGFSA-N

SMILES: C([C@H](CC(C)C)N)(=O)[C@@]1(C)CO1.C(C(O)=O)(F)(F)F

Synonyms:

• (2R)-2-[(2S)-2-Amino-4-methylpentanoyl]-2-methyloxirane trifluoroacetate
• (S)-2-amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one trifluoroacetate
• 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1)
• 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyloxiranyl]-, (2S)-,trifluoroacetate
• Carfilzomib intermediate

1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1)

CAS: 247068-85-5

Formula: C₁₁H₁₈F₃NO₄

Purity: %

Color and Shape: Solid

Molecular weight: 285.2601

Ref: IN-DA002P3Q

Carfilzomib Impurity 31 Trifluoroacetate

CAS: 247068-85-5

Formula: C₉H₁₇NO₂·C₂HF₃O₂

Molecular weight: 171.24 114.02

Ref: 4Z-C-121084

(2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate

Controlled Product

CAS: 247068-85-5

Applications (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References Xiao, Q., et al.: Process for preparation of carfilzomib, China Patent 104710507, Jun 17, 2015; Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)

Formula: C₉H₁₇NO₂·C₂HF₃O₂

Color and Shape: Neat

Molecular weight: 171.24 + 114.02

Ref: TR-A612145

Carfilzomib Impurity 24

CAS: 247068-85-5

Formula: C₉H₁₇NO₂C₂HF₃O₂

Molecular weight: 171.24 : 114.0

Ref: ST-EA-CP-C153026

(2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone trifluoroacetate

Controlled Product

CAS: 247068-85-5

Please enquire for more information about (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₉H₁₇NO₂•C₂HF₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 285.26 g/mol

Ref: 3D-FA100028