CAS 248282-01-1

Paquinimod

Description:

Paquinimod is a small molecule with immunomodulatory properties, primarily investigated for its potential therapeutic effects in autoimmune diseases and certain cancers. It functions as a selective inhibitor of the S100A9 protein, which plays a role in inflammatory processes. Paquinimod is characterized by its ability to modulate immune responses, potentially reducing inflammation and altering the activity of immune cells. The compound is typically administered orally and has been studied in clinical trials for conditions such as systemic lupus erythematosus and multiple sclerosis. Its chemical structure includes a pyridine ring, contributing to its biological activity. While it has shown promise in preclinical and clinical settings, further research is necessary to fully understand its efficacy, safety profile, and mechanism of action. As with many investigational drugs, the specific pharmacokinetics and pharmacodynamics of Paquinimod are subjects of ongoing study to optimize its therapeutic potential.

Formula: C₂₁H₂₂N₂O₃

InChI: InChI=1S/C21H22N2O3/c1-4-14-10-9-13-16-17(14)19(24)18(20(25)22(16)3)21(26)23(5-2)15-11-7-6-8-12-15/h6-13,24H,4-5H2,1-3H3

InChI key: InChIKey=DIKSYHCCYVYKRO-UHFFFAOYSA-N

SMILES: OC=1C=2C(N(C)C(=O)C1C(N(CC)C3=CC=CC=C3)=O)=CC=CC2CC

Synonyms:

• N-Ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-ethyl-1-methyl-2-oxoquinoline-3-carboxamide
• N-Ethyl-N-phenyl-1,2-dihydro-5-ethyl-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide
• N,5-Diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide
• 3-Quinolinecarboxamide, N,5-diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-
• ABR 25757

Paquinimod

CAS: 248282-01-1

Formula: C₂₁H₂₂N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 350.4110

Ref: IN-DA00BJNN

N,5-Diethyl-4-Hydroxy-1-Methyl-2-Oxo-N-Phenyl-1,2-Dihydroquinoline-3-Carboxamide

CAS: 248282-01-1

N,5-Diethyl-4-Hydroxy-1-Methyl-2-Oxo-N-Phenyl-1,2-Dihydroquinoline-3-Carboxamide

Formula: C₂₁H₂₂N₂O₃

Purity: 97%

Molecular weight: 350.41

Ref: 54-OR1024185

Paquinimod

CAS: 248282-01-1

Paquinimod

Formula: C₂₁H₂₂N₂O₃

Purity: ≥95%

Molecular weight: 350.41

Ref: 54-BUP08110

Paquinimod

CAS: 248282-01-1

Paquinimod (ABR 25757) is a S100A9 inhibitor preventing S100A9 binding to TLR-4.

Formula: C₂₁H₂₂N₂O₃

Purity: 98.04% - 99.79%

Color and Shape: White Solid

Molecular weight: 350.41

Ref: TM-T7310

Paquinimod

CAS: 248282-01-1

Formula: C₂₁H₂₂N₂O₃

Molecular weight: 350.42

Ref: 4Z-L-226005

Paquinimod

CAS: 248282-01-1

A calcium-binding protein S100A9 inhibitor with immunomodulatory activity that reduces pathology in experimental collagenase-induced osteoarthritis.

Formula: C₂₁H₂₂N₂O₃

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 350.41 g/mol

Ref: 3D-BP164809

Paquinimod - Bio-X ™

CAS: 248282-01-1

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₁H₂₂N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 350.41 g/mol

Ref: 3D-BP300014

Paquinimod

CAS: 248282-01-1

N,5-Diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide

Formula: C₂₁H₂₂N₂O₃

Purity: 97%

Molecular weight: 350.41

Ref: IN-DG00799427