CAS 2489446-47-9

Formula: C22H26ClN7O2

InChI: InChI=1S/C22H26ClN7O2/c23-18-12-16(29-8-10-32-11-9-29)3-4-19(18)27-22(31)17-14-25-30-7-5-20(28-21(17)30)26-15-2-1-6-24-13-15/h3-5,7,12,14-15,24H,1-2,6,8-11,13H2,(H,26,28)(H,27,31)/t15-/m1/s1

InChI key: PCGXWBCXAWPIRK-OAHLLOKOSA-N

SMILES: C1C[C@H](CNC1)NC2=NC3=C(C=NN3C=C2)C(=O)NC4=C(C=C(C=C4)N5CCOCC5)Cl

FLT3/ITD-IN-3

CAS: 2489446-47-9

FLT3/ITD-IN-3 (Compound 19) is a potent FLT3-ITD inhibitor with IC50 values: FLT3D835Y (0.3 nM), FLT3 (0.4 nM), inhibits AML cell proliferation.

Formula: C₂₂H₂₆ClN₇O₂

Color and Shape: Solid

Molecular weight: 455.94

Ref: TM-T62824