CAS 2491-38-5

2-Bromo-1-(4-hydroxyphenyl)ethanone

Description:

2-Bromo-1-(4-hydroxyphenyl)ethanone, with the CAS number 2491-38-5, is an organic compound characterized by its bromine and hydroxy functional groups attached to a phenyl ring. This compound features a ketone functional group, which contributes to its reactivity and potential applications in organic synthesis. The presence of the bromine atom enhances its electrophilic character, making it useful in various substitution reactions. The hydroxy group provides additional hydrogen bonding capabilities, which can influence its solubility and interaction with other molecules. Typically, compounds like this may exhibit biological activity, making them of interest in medicinal chemistry. Its molecular structure suggests that it may participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The compound is likely to be a solid at room temperature and may have moderate solubility in organic solvents. Safety precautions should be taken when handling this substance, as it may pose health risks due to the presence of bromine and other reactive functional groups.

Formula: C₈H₇BrO₂

InChI: InChI=1S/C8H7BrO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,10H,5H2

InChI key: InChIKey=LJYOFQHKEWTQRH-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC=C(O)C=C1

Synonyms:

• 1-(4-Hydroxyphenyl)-2-bromoethanone
• 2-Bromo-1-(4-Hydroxyphenyl)Ethanone
• 2-Bromo-1-(4-hydroxyphenyl)ethan-1-one
• 2-Bromo-4'-Hydroxy Acetophenone
• 2-Bromo-4'-Hydroxyacetophenone
• 4-Hydroxyphenacyl bromide
• 4′-Hydroxy-2-bromoacetophenone
• Acetophenone, 2-bromo-4′-hydroxy-
• Busan 1130
• Busan 90
• Butrol 1130
• Ethanone, 2-bromo-1-(4-hydroxyphenyl)-
• p-Hydroxyphenacyl bromide
• Α-Bromo-Hydroxyacetophenone
• α-Bromo-1-(4-hydroxyphenyl)-ethanone
• α-Bromo-4-Hydroxy Acetophenone
• α-Bromo-4′-hydroxyacetophenone
• α-Bromo-p-hydroxyacetophenone

2-Bromo-4'-hydroxyacetophenone

CAS: 2491-38-5

Formula: C₈H₇BrO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 215.05

Ref: 3B-B4115

Ethanone, 2-bromo-1-(4-hydroxyphenyl)-

CAS: 2491-38-5

Formula: C₈H₇BrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.0440

Ref: IN-DA002PUF

4-Hydroxyphenacyl bromide

CAS: 2491-38-5

4-Hydroxyphenacyl bromide

Formula: C₈H₇BrO₂

Purity: 97%

Color and Shape: off white to faint brown powder

Molecular weight: 215.04398g/mol

Ref: 54-OR11266

2-Bromo-4'-hydroxyacetophenone

CAS: 2491-38-5

2-Bromo-4'-hydroxyacetophenone

Purity: ≥98%

Molecular weight: 215.04g/mol

Ref: 54-BUP18685

Isavuconazole Impurity 48

CAS: 2491-38-5

Formula: C₈H₇BrO₂

Molecular weight: 215.05

Ref: 4Z-I-070050

2-Bromo-4'-hydroxyacetophenone

CAS: 2491-38-5

2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, PTP inhibitor that covalently blocks the catalytic domain of the SHP-1(ΔSH2).

Formula: C₈H₇BrO₂

Purity: 98.64%

Color and Shape: Clear Colorless To Light Yellow Liquid

Molecular weight: 215.04

Ref: TM-T7084

2-Bromo-4-hydroxyacetophenone

CAS: 2491-38-5

2-Bromo-4-hydroxyacetophenone is a membrane permeable inhibitor of monoamine oxidase (MAO) that has been shown to inhibit the enzyme's activity with an IC50 of 10 μM. It is used as a research tool in biological studies and has been shown to be active against MAO A, MAO B, and MAO C. 2-Bromo-4-hydroxyacetophenone has also been shown to inhibit the growth of carcinoma cells in vitro. This molecule is also a β-unsaturated ketone that binds to catalytic domains and forms covalent bonds with chloride ions. 2-Bromo-4-hydroxyacetophenone can be used as an industrial process catalyst for chemical reactions involving chloride.
2-Bromo-4-hydroxyacetophenone synergistically inhibits the growth of cancer cells when combined with other compounds such as trifluoroacetic acid or dichloromet

Formula: C₈H₇BrO₂

Purity: (%) Min. 85%

Color and Shape: Powder

Molecular weight: 215.04 g/mol

Ref: 3D-FB16431

2-Bromo-4′-hydroxyacetophenone

CAS: 2491-38-5

Formula: C₈H₇BrO₂

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 215.046

Ref: 10-F221680

2-Bromo-4'-hydroxyacetophenone

Controlled Product

CAS: 2491-38-5

Stability Hygroscopic
Applications A covalent inhibitor of protein tyrosine phosphatases (PTPs)
References Taing, M., et al.: Biochem., 38, 3793 1999, Arabaci, G., et al.: Bioorg. Med. Chem. Lett., 12, 3047 (2002),

Formula: C₈H₇BrO₂

Color and Shape: Neat

Molecular weight: 215.04

Ref: TR-B684450