CAS 2499966-67-3

Formula: C21H23F3N6O

InChI: InChI=1S/C21H23F3N6O/c1-30-9-8-12-10-15(6-7-16(12)19(30)31)28-20-26-11-17(21(22,23)24)18(29-20)27-14-4-2-13(25)3-5-14/h6-11,13-14H,2-5,25H2,1H3,(H2,26,27,28,29)

InChI key: LSEAQLOYCHTEOK-UHFFFAOYSA-N

SMILES: CN1C=CC2=C(C1=O)C=CC(=C2)NC3=NC=C(C(=N3)NC4CCC(CC4)N)C(F)(F)F

FLT3-IN-12

CAS: 2499966-67-3

FLT3-IN-12: potent, selective oral FLT3 inhibitor; FLT3-WT IC50: 1.48 nM, FLT3-D835Y: 2.87 nM; >1000x selective over c-KIT; anti-AML, IC50: 0.75 nM MV4-11.

Formula: C₂₁H₂₃F₃N₆O

Color and Shape: Solid

Molecular weight: 432.44

Ref: TM-T62412