CAS 25046-79-1

Glisoxepide

Description:

Glisoxepide is a chemical compound primarily recognized for its role as an antidiabetic agent. It belongs to the class of sulfonylureas, which are commonly used to manage blood glucose levels in individuals with type 2 diabetes. The compound functions by stimulating insulin secretion from the pancreatic beta cells, thereby enhancing glucose uptake by tissues. Glisoxepide is characterized by its ability to lower blood sugar levels effectively while also exhibiting a relatively favorable side effect profile compared to some other antidiabetic medications. Its chemical structure includes a sulfonylurea moiety, which is essential for its biological activity. Additionally, Glisoxepide has been studied for its potential effects on lipid metabolism and cardiovascular health, making it a compound of interest in diabetes management. As with any medication, its use should be guided by healthcare professionals, considering individual patient needs and potential interactions with other medications.

Formula: C₂₀H₂₇N₅O₅S

InChI: InChI=1/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)

InChI key: InChIKey=ZKUDBRCEOBOWLF-UHFFFAOYSA-N

SMILES: S(NC(NN1CCCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C3=NOC(C)=C3)C=C2

Synonyms:

• 4-[4-[β-(5-Methylisoxazole-3-carboxamido)ethyl]phenylsulfonyl]-1,1-hexamethylenesemicarbazide
• Bs 4231
• Glisepin
• Glisoxepid
• Glisoxepida
• Glisoxepide
• N-[2-[4-[[[[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-3-isoxazolecarboxamide
• Pro-Diaban
• Pro-Diaben
• Rp 22410
• Urea, 1-(hexahydro-1H-azepin-1-yl)-3-[[p-[2-(5-methyl-3-isoxazolecarboxamido)ethyl]phenyl]sulfonyl]-
• Glisoxepida [Spanish]
• BRN 0592109
• N-(2-{4-[(azepan-1-ylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-1,2-oxazole-3-carboxamide
• Bay B 4231
• 3-Isoxazolecarboxamide, N-(2-(4-(((((hexahydro-1H-azepin-1-yl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-
• UNII-H7SC0I332I
• FBB 4231
• Glisoxepidum
• Glisoxepide [INN:BAN:DCF]
• 1-(Hexahydro-1H-azepin-1-yl)-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)urea
• Glisoxepida [INN-Spanish]
• Glisoxepidum [INN-Latin]
• 3-Isoxazolecarboxamide, N-[2-[4-[[[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-
• Glisoxepid (10mM in DMSO)

Glisoxepid

Controlled Product

CAS: 25046-79-1

Applications Glisoxepid is used as an antidiabetic drug. Glisoxepid is a sulfonylurea derivative used in the treatment of diabetes mellitus type 2.
References Schulz, M., et al.: Pharmazie, 58, 447 (2003), Viswanathan, C., et al.: Pharm. Res., 24, 1962 (2007), Drees, J., et al.: Clin. Chem., 55, 126 (2009),

Formula: C₂₀H₂₇N₅O₅S

Color and Shape: Neat

Molecular weight: 449.52

Ref: TR-G410600

Glisoxepide

CAS: 25046-79-1

Glisoxepide: sulphonamide, oral K(ATP) blocker, antihyperglycemic, affects heart.

Formula: C₂₀H₂₇N₅O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 449.52

Ref: TM-T15386