CAS 2507-61-1: (4R)-4-Fluoro-L-proline

Description: (4R)-4-Fluoro-L-proline is a fluorinated derivative of proline, an amino acid that plays a crucial role in protein synthesis and structure. This compound features a fluorine atom substituted at the fourth carbon of the proline backbone, which can influence its biological activity and interactions. The presence of the fluorine atom can enhance the stability and lipophilicity of the molecule, potentially affecting its pharmacokinetic properties. (4R)-4-Fluoro-L-proline is often utilized in medicinal chemistry and drug design, particularly in the development of peptide-based therapeutics, due to its ability to introduce conformational constraints in peptide chains. Its chirality, indicated by the (4R) designation, is significant as it can affect the compound's interaction with biological targets. The compound is typically characterized by its molecular formula, melting point, solubility, and spectral data, which are essential for its identification and application in research. Overall, (4R)-4-Fluoro-L-proline serves as an important building block in the synthesis of various bioactive molecules.

Formula: C₅H₈FNO₂

InChI: InChI=1S/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

InChI key: InChIKey=ZIWHMENIDGOELV-DMTCNVIQSA-N

SMILES: O=C(O)C1NCC(F)C1

Synonyms:

• (4R)-4-Fluoro-L-proline
• L-Proline, 4-fluoro-, trans-
• Proline, 4-fluoro-, L-trans-
• trans-4-Fluoro-L-proline
• L-Proline, 4-fluoro-, (4R)-

trans-4-Fluoro-L-proline

CAS: 2507-61-1

• Formula: C₅H₈FNO₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 133.12

H-trans-4-Fluoro-Pro-OH

CAS: 2507-61-1

(2S,4R)-4-Fluoroproline-containing ubiquitin can be expressed in auxotrophic Escherichia coli strains. The trans isomer of 4-fluoroproline …

• Formula: C₅H₈FNO₂
• Purity: > 99%
• Color and Shape: White Crystalline
• Molecular weight: 133.12

L-Proline, 4-fluoro-, (4R)-

CAS: 2507-61-1

• Formula: C₅H₈FNO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 133.1209

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2507-61-1

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 133.1219940185547

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2507-61-1

• Purity: 98%
• Molecular weight: 133.12g/mol

trans-4-Fluoropyrrolidine-2-carboxylic Acid-13C1 Hydrochloride Salt

CAS: 2507-61-1

Applications trans-4-Fluoropyrrolidine-2-carboxylic Acid-13C1 Hydrochloride Salt is an isotopic analog of (2S,4R)-4-Fluoropyrrolidine-2-carboxylic Acid (F594640).

• Formula: C₄CH₈FNO₂•HCl
• Color and Shape: Neat
• Molecular weight: 134.11+(36.46)

(2S,4R)-4-Fluoro-pyrrolidine-2-carboxylic acid

CAS: 2507-61-1

(2S,4R)-4-Fluoro-pyrrolidine-2-carboxylic acid is a synthetic molecule that has been shown to inhibit the biosynthesis of …

• Formula: C₅H₈FNO₂
• Purity: Min. 95%
• Molecular weight: 133.12 g/mol