CAS 2507-61-1

(4R)-4-Fluoro-L-proline

Description:

(4R)-4-Fluoro-L-proline is a fluorinated derivative of proline, an amino acid that plays a crucial role in protein synthesis and structure. This compound features a fluorine atom substituted at the fourth carbon of the proline backbone, which can influence its biological activity and interactions. The presence of the fluorine atom can enhance the stability and lipophilicity of the molecule, potentially affecting its pharmacokinetic properties. (4R)-4-Fluoro-L-proline is often utilized in medicinal chemistry and drug design, particularly in the development of peptide-based therapeutics, due to its ability to introduce conformational constraints in peptide chains. Its chirality, indicated by the (4R) designation, is significant as it can affect the compound's interaction with biological targets. The compound is typically characterized by its molecular formula, melting point, solubility, and spectral data, which are essential for its identification and application in research. Overall, (4R)-4-Fluoro-L-proline serves as an important building block in the synthesis of various bioactive molecules.

Formula: C₅H₈FNO₂

InChI: InChI=1S/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

InChI key: InChIKey=ZIWHMENIDGOELV-DMTCNVIQSA-N

SMILES: C(O)(=O)[C@@H]1C[C@@H](F)CN1

Synonyms:

• (4R)-4-Fluoro-L-proline
• L-Proline, 4-fluoro-, trans-
• Proline, 4-fluoro-, L-trans-
• trans-4-Fluoro-L-proline
• L-Proline, 4-fluoro-, (4R)-

trans-4-Fluoro-L-proline

CAS: 2507-61-1

Formula: C₅H₈FNO₂

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 133.12

Ref: 3B-F0818

H-trans-4-Fluoro-Pro-OH

CAS: 2507-61-1

(2S,4R)-4-Fluoroproline-containing ubiquitin can be expressed in auxotrophic Escherichia coli strains. The trans isomer of 4-fluoroproline stabilizes the protein structure due to a pre-organization effect. 21156-44-5

Formula: C₅H₈FNO₂

Purity: > 99%

Color and Shape: White Crystalline

Molecular weight: 133.12

Ref: 01-4033275

L-Proline, 4-fluoro-, (4R)-

CAS: 2507-61-1

Formula: C₅H₈FNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 133.1209

Ref: IN-DA002QDO

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2507-61-1

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

Formula: C₅H₈FNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 133.12092

Ref: 54-PC5718

H-trans-4-F-L-Pro-OH

CAS: 2507-61-1

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

Formula: C₅H₈FNO₂

Purity: 97%

Molecular weight: 133.12

Ref: IN-DG32616

(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2507-61-1

Formula: C₅H₈FNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 133.122

Ref: 10-F430311

trans-4-Fluoropyrrolidine-2-carboxylic Acid-13C1 Hydrochloride Salt

Controlled Product

CAS: 2507-61-1

Applications trans-4-Fluoropyrrolidine-2-carboxylic Acid-13C1 Hydrochloride Salt is an isotopic analog of (2S,4R)-4-Fluoropyrrolidine-2-carboxylic Acid (F594640).

Formula: C₄CH₈FNO₂•HCl

Color and Shape: Neat

Molecular weight: 134.11+(36.46)

Ref: TR-F594642

(2S,4R)-4-Fluoro-pyrrolidine-2-carboxylic acid

CAS: 2507-61-1

(2S,4R)-4-Fluoro-pyrrolidine-2-carboxylic acid is a synthetic molecule that has been shown to inhibit the biosynthesis of collagen. It has also been found to have antimicrobial properties and an ability to prevent Gram-negative bacterial infections by inhibiting the synthesis of bioactive molecules. The chemical stability of (2S,4R)-4-fluoropyrrolidine-2-carboxylic acid makes it suitable for in vitro studies and as a precursor for other compounds. This compound can be prepared through asymmetric synthesis with gramicidin or chloromethyl ketone as starting materials.

Formula: C₅H₈FNO₂

Purity: Min. 95%

Molecular weight: 133.12 g/mol

Ref: 3D-FF56097