CAS 25126-32-3: (27-tyr(so(3)H))cholecystokinin-fragment (26-33)-amide
Description:The chemical substance known as "(27-tyr(so(3)H))cholecystokinin-fragment (26-33)-amide," with the CAS number 25126-32-3, is a peptide fragment derived from cholecystokinin (CCK), a hormone involved in digestion and satiety. This specific fragment consists of amino acids 26 to 33 of the CCK molecule, with a sulfated tyrosine at position 27, which is crucial for its biological activity. The presence of the sulfate group enhances the peptide's interaction with its receptors, influencing various physiological processes such as gallbladder contraction and enzyme secretion from the pancreas. The structure of this peptide includes a sequence of amino acids linked by peptide bonds, and it exhibits properties typical of peptides, such as solubility in water and stability under physiological conditions. Its biological significance is underscored by its role in the gastrointestinal system, making it a subject of interest in studies related to digestion, appetite regulation, and potential therapeutic applications in gastrointestinal disorders.
Formula:C49H62N10O16S3
InChI:InChI=1/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
- Synonyms:
- (tyr(so3H)27)-cholecystokinin fragment*26-33 amid
- Sincalide
- Cholecystokinin Octapeptide
- Tyr(SO3H]27)Cholecystokinin fragment 26-33 Amide
- alpha-aspartyl-O-sulfotyrosylmethionylglycyltryptophylmethionyl-alpha-aspartylphenylalaninamide
- L-alpha-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide
- Sincalide(CCK-8)
- Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
- Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-5-L-methionine-
- Cholecystokinin C-terminal octapeptide
- See more synonyms
- Cholecystokinin octapeptide (26-33 sulfated)
- Cholecystokinin-(26-33)-amide
- Cholecystokinin-8 (chicken)
- Cholecystokinin-8 (pig)
- Cholecystokinin-8 (Squalus acanthias)
- Cholecystokinin-8 (swine)
- Cholecystokinin-pancreozymin (swine intestine C-terminal octapeptide)
- Cholecystokinin-pancreozymin C-terminal octapeptide
- Human CCK-8
- L-Phenylalaninamide, L-α-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-
- Sincalid
- Sincalida
- Sq 19844