CAS 252049-05-1: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-norvaline
Description:N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-norvaline, commonly referred to as Fmoc-N-methyl-L-norvaline, is a chemical compound primarily used in peptide synthesis as a protecting group for amino acids. The Fmoc (9-fluorenylmethoxycarbonyl) group is a widely utilized protective group in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under mild acidic conditions. This compound features a norvaline backbone, which is an amino acid derivative, and the methyl group on the nitrogen enhances its steric properties, influencing its reactivity and solubility. The presence of the fluorenyl group contributes to its hydrophobic characteristics, making it useful in various organic synthesis applications. Additionally, the compound's structure allows for specific interactions in biological systems, making it of interest in medicinal chemistry and drug design. Overall, Fmoc-N-methyl-L-norvaline is a valuable tool in the synthesis of peptides and other complex organic molecules.
Formula:C21H23NO4
InChI:InChI=1S/C21H23NO4/c1-3-8-19(20(23)24)22(2)21(25)26-13-18-16-11-6-4-9-14(16)15-10-5-7-12-17(15)18/h4-7,9-12,18-19H,3,8,13H2,1-2H3,(H,23,24)/t19-/m0/s1
InChI key:InChIKey=HKELUUGCKFRJQM-IBGZPJMESA-N
SMILES:O=C(O)C(N(C(=O)OCC1C=2C=CC=CC2C=3C=CC=CC31)C)CCC
- Synonyms:
- <span class="text-smallcaps">L</span>-Norvaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- Fmoc-L-Mench[Ch3(Ch2)2]-Cooh
- Fmoc-L-Menva-Oh
- Fmoc-L-N-Methyl-2-Aminovaleric Acid
- Fmoc-Menva-Oh
- Fmoc-N-Me-Nva-OH
- Fmoc-N-methyl-L-norvaline
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-L-2-Aminopentanoic Acid
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-L-Norvaline
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-Norvaline
- See more synonyms
- N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Alpha-Methyl-L-Norvaline
- N-Alpha-Fmoc-N-Alpha-Methyl-L-Norvaline
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-norvaline
- L-Norvaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-norvaline