CAS 252186-79-1

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide

Description:

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide, with CAS number 252186-79-1, is a chemical compound characterized by its complex structure, which includes a triazine ring and multiple chlorinated aromatic groups. This compound typically exhibits properties associated with both triazine derivatives and chlorinated aromatic compounds, such as potential biological activity and stability under various conditions. The presence of amino and chlorinated substituents suggests that it may engage in hydrogen bonding and exhibit lipophilicity, which can influence its solubility and reactivity. Such compounds are often studied for their potential applications in pharmaceuticals, agrochemicals, or as intermediates in organic synthesis. Additionally, the specific arrangement of functional groups can impart unique properties, making it of interest in medicinal chemistry and material science. Safety and handling precautions are essential due to the presence of chlorine, which can pose environmental and health risks.

Formula: C₁₆H₉Cl₄N₅O

InChI: InChI=1S/C16H9Cl4N5O/c17-9-5-1-3-7(11(9)19)13-14(21)22-16(25-24-13)23-15(26)8-4-2-6-10(18)12(8)20/h1-6H,(H3,21,22,23,25,26)

InChI key: InChIKey=RDUGDEWOUWFKPL-UHFFFAOYSA-N

SMILES: NC=1C(=NN=C(NC(=O)C2=C(Cl)C(Cl)=CC=C2)N1)C3=C(Cl)C(Cl)=CC=C3

Synonyms:

• Benzamide, N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichloro-
• N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
• Lamotrigine Related Compound D (N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorob (1356790)
• Lamotrigine Related Compound D (10 mg) (N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide)
• LaMotrigine EP IMpurity-B
• Lamotrigine impurity F (PhEur)
• Lamotrigine Impurity 5 (Lamotrigine EP Impurity F)
• Lamotrigine Related Compound D (USP)
• Lamotrigine EP Impurity F/ Lamotrigine Related Compound D
• Lamotrigine USP Related Compound D
• Lamotrigine EP impurity F
• Lamotrigine Impurity F
• LaMotrigine EP IMpurity-F (USP RC D)

Lamotrigine Related Compound D (N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide)

CAS: 252186-79-1

Compounds (excluding melamine) containing an unfused triazine ring (whether or not hydrogenated) in the structure

Formula: C₁₆H₉Cl₄N₅O

Color and Shape: White Powder

Molecular weight: 426.95612

Ref: 45-1356790

Lamotrigine EP Impurity F (Lamotrigine USP Related Compound D)

CAS: 252186-79-1

Formula: C₁₆H₉Cl₄N₅O

Color and Shape: Yellow Solid

Molecular weight: 429.08

Ref: 4Z-L-015

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide

CAS: 252186-79-1

Color and Shape: Neat

Ref: 86-MM0922.06

Lamotrigine EP Impurity F

CAS: 252186-79-1

Formula: C₁₆H₉Cl₄N₅O

Molecular weight: 429.09

Ref: ST-EA-CP-L10006

3-(2,3-Dichlorobenzamido) Lamotrigine

CAS: 252186-79-1

Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D
Stability Light Sensitive
Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);

Formula: C₁₆H₉Cl₄N₅O

Color and Shape: Neat

Molecular weight: 429.09

Ref: TR-D431860

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide

CAS: 252186-79-1

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.

Formula: C₁₆H₉Cl₄N₅O

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 429.09 g/mol

Ref: 3D-IA58055