CAS 252916-29-3: Orantinib

Description: Orantinib, with the CAS number 252916-29-3, is a small molecule that functions primarily as a tyrosine kinase inhibitor. It is designed to target specific pathways involved in tumor growth and angiogenesis, making it a candidate for cancer treatment. The compound exhibits a unique chemical structure that allows it to interact with various kinases, thereby inhibiting their activity and potentially slowing down the progression of certain cancers. Orantinib has shown promise in preclinical studies and clinical trials, particularly in the context of solid tumors. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are critical for determining its efficacy and safety profile. Additionally, like many targeted therapies, it may have a range of side effects, which necessitates careful monitoring during treatment. Overall, Orantinib represents a significant advancement in the development of targeted cancer therapies, reflecting ongoing research efforts in the field of oncology.

Formula: C₁₈H₁₈N₂O₃

InChI: InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)

InChI key: InChIKey=NHFDRBXTEDBWCZ-UHFFFAOYSA-N

SMILES: O=C(O)CCC1=C(NC(C=C2C(=O)NC=3C=CC=CC32)=C1C)C

Synonyms:

• 1H-Pyrrole-3-propanoic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
• 3-[2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic acid
• 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic acid
• 3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone
• 3-{2,4-dimethyl-5-[(E)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid
• 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
• NSC 702827
• Orantinib
• Su-6668
• Tsu-68

1H-Pyrrole-3-propanoicacid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-

CAS: 252916-29-3

• Formula: C₁₈H₁₈N₂O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 310.3471

Orantinib

CAS: 252916-29-3

• Purity: 98%
• Molecular weight: 310.35g/mol

Orantinib

CAS: 252916-29-3

Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, …

• Formula: C₁₈H₁₈N₂O₃
• Purity: 100% - 98.01%
• Color and Shape: Solid
• Molecular weight: 310.35

Orantinib

CAS: 252916-29-3

TSU-68

CAS: 252916-29-3

Applications TSU-68 is a inhibitor that targets vascular endothelial growth factor receptor 2, platelet-derived growth …

• Formula: C₁₈H₁₈N₂O₃
• Color and Shape: Neat
• Molecular weight: 310.35

TSU-68

CAS: 252916-29-3

Inhibitor of multiple tyrosine kinases

• Formula: C₁₈H₁₈N₂o₃
• Purity: Min. 95%

TSU-68

CAS: 252916-29-3

• Purity: 95%
• Molecular weight: 310.353