CAS: 252917-06-9 - 6-[2-[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3-carbonitrile

Formula: C₂₂H₁₈Cl₂N₈

InChI: InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)

InChI key: InChIKey=AQGNHMOJWBZFQQ-UHFFFAOYSA-N

SMILES: N#CC1=CN=C(C=C1)NCCNC=2N=CC(C3=NC=C(N3)C)=C(N2)C=4C=CC(Cl)=CC4Cl

Synonyms:

• 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-
• 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-
• 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
• Chir 911
• Chir 99201
• Chir-99021
• Chir99021
• Cihr 99021
• Ct 99021
• GSK 3 inhibitor XVI
• Gsk 3Ixv
• Laduviglusib

CHIR 99021

CAS: 252917-06-9

• Formula: C₂₂H₁₈Cl₂N₈
• Purity: >97.0%(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 465.34

CHIR 99021-d4

CAS: 252917-06-9

• Formula: C₂₂H₁₄D₄Cl₂N₈
• Molecular weight: 469.37

CHIR 99021

CAS: 252917-06-9

• Formula: C₂₂H₁₈Cl₂N₈
• Molecular weight: 465.34

CHIR99021

CAS: 252917-06-9

• Formula: C₂₂H₁₈Cl₂N₈
• Purity: By hplc: >99% (Typical Value in Batch COA)
• Color and Shape: off-white to beige solid
• Molecular weight: 465.34g/mol

CHIR-99021

CAS: 252917-06-9

CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 …

• Formula: C₂₂H₁₈Cl₂N₈
• Purity: 98.91%
• Color and Shape: Solid
• Molecular weight: 465.34

CHIR 99021 Hydrochloride Salt

CAS: 252917-06-9

Applications CHIR 99021 Hydrochloride is an inhibitor of glycogen synthase kinase 3, which mimics Wnt …

• Formula: C₂₂H₁₈Cl₂N₈•xHCl
• Color and Shape: Pale Yellow to Light Yellow Solid
• Molecular weight: 465.343646

CHIR 99021

CAS: 252917-06-9

Potent and selective inhibitor of the glycogen synthase kinase GSK-3. Promotes cell renewal in embryonic …

• Formula: C₂₂H₁₈Cl₂N₈
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 465.34 g/mol

CHIR-99021-d4

CAS: 252917-06-9

• Formula: C₂₂H₁₄D₄Cl₂N₈
• Molecular weight: 469.363

[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile

CAS: 252917-06-9

• Formula: C₂₂H₁₈Cl₂N₈
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 465.3379