CAS 25451-15-4

Felbamate

Description:

Felbamate is an anticonvulsant medication primarily used in the treatment of epilepsy, particularly for patients who have not responded adequately to other treatments. It is classified as a carbamate derivative and has a unique mechanism of action that involves the modulation of the NMDA receptor and the enhancement of GABAergic activity, which helps stabilize neuronal excitability. Felbamate is known for its potential to cause serious side effects, including aplastic anemia and liver failure, which necessitates careful monitoring of patients. The substance is typically administered orally and is available in various formulations, including tablets and oral suspension. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for less frequent dosing. Felbamate's efficacy in reducing seizure frequency has made it a valuable option for certain patients, although its use is often limited due to the risk of severe adverse effects. As with any medication, it is essential for healthcare providers to weigh the benefits against the risks when considering felbamate for treatment.

Formula: C₁₁H₁₄N₂O₄

InChI: InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15)

InChI key: InChIKey=WKGXYQFOCVYPAC-UHFFFAOYSA-N

SMILES: C(COC(N)=O)(COC(N)=O)C1=CC=CC=C1

Synonyms:

• 1,3-Bis(carbamoyloxy)-2-phenylpropane
• 1,3-Propanediol, 2-phenyl-, 1,3-dicarbamate
• 1,3-Propanediol, 2-phenyl-, dicarbamate
• 2-Phenyl-1,3-propanediol dicarbamate
• 2-Phenylpropan-1,3-diyldicarbamat
• 2-Phenylpropane-1,3-diyl dicarbamate
• Add 03055
• Brn 3345236
• Carbamic acid, 2-phenyltrimethylene ester
• Dicarbamate De 2-Phenylpropane-1,3-Diyle
• Dicarbamato De 2-Fenilpropano-1,3-Diilo
• Felbamato
• Felbamato [Spanish]
• Felbamatum
• Felbamatum [Latin]
• Felbamyl
• Felbatol
• Hsdb 7525
• Taloxa
• Unii-X72Rbb02N8
• W 554
• 4-06-00-05993 (Beilstein Handbook Reference)

Felbamate

CAS: 25451-15-4

Formula: C₁₁H₁₄N₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 238.24

Ref: 3B-F1039

Felbamate

CAS: 25451-15-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₁H₁₄N₂O₄

Color and Shape: White Off-White Powder

Molecular weight: 238.09536

Ref: 45-1269312

(3-carbamoyloxy-1,1,3,3-tetradeuterio-2-phenylpropyl) carbamate

CAS: 25451-15-4

Formula: C₁₁H₁₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.2399

Ref: IN-DA00I4UR

Felbamate

CAS: 25451-15-4

Formula: C₁₁H₁₄N₂O₄

Purity: ≥ 98.0None

Color and Shape: White to off-white solid

Molecular weight: 238.24

Ref: 7W-GP1193

Felbamate

CAS: 25451-15-4

Formula: C₁₁H₁₄N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 238.24

Ref: 4Z-F-411

Felbamate

CAS: 25451-15-4

Felbamate

Purity: ≥98%

Molecular weight: 238.24g/mol

Ref: 54-BUP10711

Felbamate

CAS: 25451-15-4

Felbamate

Purity: 98%

Molecular weight: 238.24g/mol

Ref: 54-OR1026239

Felbamate

CAS: 25451-15-4

Felbamate (W-554) is an Anti-epileptic Agent.

Formula: C₁₁H₁₄N₂O₄

Purity: 99% - >99.99%

Color and Shape: White Powder Solid

Molecular weight: 238.24

Ref: TM-T1946

2-Phenylpropane-1,3-diyl dicarbamate

CAS: 25451-15-4

Purity: 95.0%

Molecular weight: 238.2429962158203

Ref: 10-F229112

Felbamate

Controlled Product

CAS: 25451-15-4

Applications Antiepileptic, structurally similar to meprobamate.
References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),

Formula: C₁₁H₁₄N₂O₄

Color and Shape: Neat

Molecular weight: 238.24

Ref: TR-F231000

Felbamate-d5

Controlled Product

CAS: 25451-15-4

Formula: C₁₅H₁₇D₅N₂O₄

Color and Shape: Neat

Molecular weight: 299.38

Ref: TR-F231003