CAS 25451-15-4
:Felbamate
Description:
Felbamate is an anticonvulsant medication primarily used in the treatment of epilepsy, particularly for patients who have not responded adequately to other treatments. It is classified as a carbamate derivative and has a unique mechanism of action that involves the modulation of the NMDA receptor and the enhancement of GABAergic activity, which helps stabilize neuronal excitability. Felbamate is known for its potential to cause serious side effects, including aplastic anemia and liver failure, which necessitates careful monitoring of patients. The substance is typically administered orally and is available in various formulations, including tablets and oral suspension. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for less frequent dosing. Felbamate's efficacy in reducing seizure frequency has made it a valuable option for certain patients, although its use is often limited due to the risk of severe adverse effects. As with any medication, it is essential for healthcare providers to weigh the benefits against the risks when considering felbamate for treatment.
Formula:C11H14N2O4
InChI:InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15)
InChI key:InChIKey=WKGXYQFOCVYPAC-UHFFFAOYSA-N
SMILES:C(COC(N)=O)(COC(N)=O)C1=CC=CC=C1
Synonyms:- 1,3-Bis(carbamoyloxy)-2-phenylpropane
- 1,3-Propanediol, 2-phenyl-, 1,3-dicarbamate
- 1,3-Propanediol, 2-phenyl-, dicarbamate
- 2-Phenyl-1,3-propanediol dicarbamate
- 2-Phenylpropan-1,3-diyldicarbamat
- 2-Phenylpropane-1,3-diyl dicarbamate
- Add 03055
- Brn 3345236
- Carbamic acid, 2-phenyltrimethylene ester
- Dicarbamate De 2-Phenylpropane-1,3-Diyle
- Dicarbamato De 2-Fenilpropano-1,3-Diilo
- Felbamato
- Felbamato [Spanish]
- Felbamatum
- Felbamatum [Latin]
- Felbamyl
- Felbatol
- Hsdb 7525
- Taloxa
- Unii-X72Rbb02N8
- W 554
- 4-06-00-05993 (Beilstein Handbook Reference)
- See more synonyms
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Felbamate
CAS:Formula:C11H14N2O4Purity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:238.24Felbamate
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof, nesoiFormula:C11H14N2O4Color and Shape:White Off-White PowderMolecular weight:238.09536Felbamate
CAS:Formula:C11H14N2O4Purity:≥ 98.0NoneColor and Shape:White to off-white solidMolecular weight:238.24Felbamate
CAS:Controlled ProductApplications Antiepileptic, structurally similar to meprobamate.
References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),Formula:C11H14N2O4Color and Shape:NeatMolecular weight:238.242-Phenylpropane-1,3-diyl dicarbamate
CAS:2-Phenylpropane-1,3-diyl dicarbamateFormula:C11H14N2O4Purity:98%Molecular weight:238.24Felbamate
CAS:Felbamate (W-554) is an Anti-epileptic Agent.Formula:C11H14N2O4Purity:98.10% - >99.99%Color and Shape:White SolidMolecular weight:238.24
