CAS 256373-96-3

CP-456773 sodium

Description:

CP-456773 sodium, identified by its CAS number 256373-96-3, is a chemical compound that functions primarily as a selective inhibitor of certain protein kinases, particularly those involved in cellular signaling pathways. This compound is often studied for its potential therapeutic applications, particularly in the context of cancer treatment, due to its ability to modulate cell proliferation and survival. In terms of its chemical characteristics, CP-456773 sodium is typically presented as a sodium salt, which enhances its solubility in aqueous solutions, making it suitable for biological assays. The compound exhibits a specific molecular structure that allows it to interact with target proteins effectively, influencing their activity. Additionally, it is important to handle CP-456773 sodium with care, as with many chemical substances, due to potential toxicity and the need for proper safety protocols during experimentation. Overall, CP-456773 sodium represents a significant area of research in medicinal chemistry, particularly in the development of targeted therapies.

Formula: C₂₀H₂₃N₂NaO₅S

InChI: InChI=1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q;+1/p-1

InChI key: LFQQNXFKPNZRFT-UHFFFAOYSA-M

SMILES: CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+]

Synonyms:

• CP-456773 SODIUM; CRID3 SODIUM SALT; MCC-950 SODIUM; CP456773 SODIUM; CRID-3 SODIUM SALT
• Crid3 sodium
• MCC950 (CP-456773) sodium
• CP-456773 sodium salt >=98% (HPLC)
• MCC950 sodium (CP-456773 sodium
• CP-456773 sodium salt
• CPD1600
• MCC-950 Sodium, CP-456773
• CP-456773 sodium
• MCC950 sodium salt
• N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide monosodium salt
• MCC950 Sodium Salt (CP-456773)
• MCC950 sodium
• CRID3 sodium salt
• MCC950(CP-456773)
• MCC 950 sodium NEW
• sodium salt of 1-(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]-urea

MCC950 Sodium Salt

CAS: 256373-96-3

Formula: C₂₀H₂₃N₂NaO₅S

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 426.46

Ref: 3B-M3396

MCC950 sodium

CAS: 256373-96-3

MCC950 sodium

Formula: C₂₀H₂₃N₂O₅S·Na

Purity: 98%

Molecular weight: 426.46178

Ref: 54-BISN0154

MCC950 sodium

CAS: 256373-96-3

MCC950 sodium

Formula: C₂₀H₂₃N₂O₅S·Na

Purity: 99.5%

Molecular weight: 426.46

Ref: 54-BUP17101

2-Furansulfonamide, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt (1:1)

CAS: 256373-96-3

Formula: C₂₀H₂₄N₂NaO₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 427.4697

Ref: IN-DA00BF7N

MCC950 sodium

CAS: 256373-96-3

MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs).

Formula: C₂₀H₂₃N₂NaO₅S

Purity: 95.49% - 99.80%

Color and Shape: Solid

Molecular weight: 426.462

Ref: TM-T6887

MCC950 sodium

CAS: 256373-96-3

Sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide

Formula: C₂₀H₂₃N₂NaO₅S

Purity: 98%

Molecular weight: 426.46

Ref: IN-DG630595

MCC950 sodium salt

CAS: 256373-96-3

Formula: C₂₀H₂₃N₂NaO₅S

Purity: ≥ 97.0%

Color and Shape: White to off-white crystalline powder or solid

Molecular weight: 426.5

Ref: 7W-GL1674

MCC950 Sodium Salt (CP-456773)

CAS: 256373-96-3

Formula: C₂₀H₂₃N₂O₅S·Na

Molecular weight: 403.47 22.99

Ref: 4Z-M-181001

MCC 950 sodium

CAS: 256373-96-3

Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.

Formula: C₂₀H₂₃N₂O₅S·Na

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 426.46 g/mol

Ref: 3D-BM163575

MCC950 sodium

CAS: 256373-96-3

Formula: C₂₀H₂₃N₂NaO₅S

Molecular weight: 426.5

Ref: BE-RMCM052001