CAS 25696-21-3

a1-14-Corticotropin

Description:

A1-14-Corticotropin, also known as adrenocorticotropic hormone (ACTH), is a peptide hormone produced by the anterior pituitary gland. It plays a crucial role in the regulation of cortisol production from the adrenal cortex, influencing various physiological processes including metabolism, immune response, and stress response. The substance is composed of a sequence of amino acids, typically consisting of 39 residues in its full-length form, with the first 14 amino acids being critical for its biological activity. A1-14-Corticotropin is characterized by its ability to bind to specific receptors on adrenal cells, stimulating the synthesis and release of glucocorticoids. It is often used in clinical settings for diagnostic purposes, particularly in assessing adrenal function and diagnosing conditions such as Addison's disease or Cushing's syndrome. The CAS number 25696-21-3 identifies this specific peptide, which is synthesized through various methods, including recombinant DNA technology. Its stability, solubility, and bioactivity are important factors in its therapeutic applications.

Formula: C₇₇H₁₀₉N₂₁O₂₀S

Synonyms:

• 1-14-Acth
• Acth(1-14)
• a-MSH (Dicentrarchus labrax)
• a-MSH (Mytilus edulis)
• a-MSH (Rana catesbeiana)
• a-MSH (chicken)
• a-MSH A (Oncorhynchus mykissreduced)
• a-Melanocyte-stimulating hormone(porcine pituitary gland anterior/intermediate lobe)
• a-Melanotropin (Dicentrarchuslabrax)
• a-Melanotropin (Mytilus edulis)
• a-Melanotropin (Rana catesbeiana)
• a-melanotropin (Danio rerio genePOMC)
• a1-14-ACTH

ACTH (1-14)

CAS: 25696-21-3

ACTH (1–14) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. ACTH (1–14) is an agonist of the melanocortin-1 and 3 receptor (K1 = 0.836 ± 0.33 and 48,3 ± 9,0 nmol/L respectively).

Formula: C₇₇H₁₀₉N₂₁O₂₀S

Purity: 97.7%

Color and Shape: White Powder

Molecular weight: 1680.91

Ref: 01-4095839

ACTH (1-14)

CAS: 25696-21-3

ACTH (1-14) is a pituitary hormone fragment that controls cortisol and androgen levels.

Formula: C₇₇H₁₀₉N₂₁O₂₀S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1680.88

Ref: TM-TP1238

ACTH (1-14) trifluoroacetate salt

CAS: 25696-21-3

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Formula: C₇₇H₁₀₉N₂₁O₂₀S

Purity: Min. 95%

Molecular weight: 1,680.88 g/mol

Ref: 3D-FA110227