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CAS 25717-80-0

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Molsidomine

Description:
Molsidomine is a pharmacologically active compound primarily used as a vasodilator in the treatment of angina pectoris and other cardiovascular conditions. It is classified as a nitric oxide donor, which means it facilitates the release of nitric oxide in the body, leading to relaxation of vascular smooth muscle and subsequent vasodilation. Molsidomine is characterized by its relatively rapid onset of action and a duration of effect that can last several hours. The compound is typically administered orally and is known for its favorable side effect profile compared to traditional nitrates, as it does not lead to tolerance with prolonged use. Chemically, molsidomine is a derivative of the amino acid L-arginine and contains a unique structure that includes a 1,2,4-oxadiazole ring. Its solubility in water is moderate, and it is generally stable under standard storage conditions. Molsidomine is also notable for its ability to improve exercise tolerance in patients with ischemic heart disease, making it a valuable therapeutic option in cardiovascular medicine.
Formula:C7H8N2O4
InChI:InChI=1/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3
InChI key:InChIKey=XLFWDASMENKTKL-UHFFFAOYSA-N
SMILES:[N-](C(OCC)=O)C1=C[N+](=NO1)N2CCOCC2
Synonyms:
  • 1,2,3-Oxadiazolium, 5-[(ethoxycarbonyl)amino]-3-(4-morpholinyl)-, inner salt
  • Cas 276
  • Corraton
  • Coruno
  • Corvasal
  • Corvaton
  • Ethoxy{[3-(Morpholin-4-Yl)-1,2,3-Oxadiazol-3-Ium-5-Yl]Imino}Methanolate
  • Moisidomine
  • Molsicor
  • Molsidolat
  • See more synonyms
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