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CAS 2576427-49-9

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    VS3

    CAS:
    VS3 is an inhibitor of the YAP-TEAD interaction. By directly binding to the TEAD4 Interface 3 (Kd = 6 μM), VS3 disrupts the interaction between YAP and TEAD. It exhibits antiproliferative activity against HT29, HCT116, and A2780 cells. VS3 is useful for studying colorectal adenocarcinoma and ovarian cancer.
    Formula:C21H21N3O3
    Molecular weight:363.42

    Ref: TM-T214392

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