CAS 2581114-83-0

Formula: C18H16F5N5O2S

InChI: InChI=1S/C18H16F5N5O2S/c1-17(5-13(18(21,22)23)31-16(24)28-17)10-4-9(2-3-11(10)20)27-15(29)12-6-26-14(7-25-12)30-8-19/h2-4,6-7,13H,5,8H2,1H3,(H2,24,28)(H,27,29)/t13-,17-/m0/s1

InChI key: JRPAQOLQALFUAQ-GUYCJALGSA-N

SMILES: C[C@]1(C[C@H](SC(=N1)N)C(F)(F)F)C2=C(C=CC(=C2)NC(=O)C3=CN=C(C=N3)OCF)F

BACE1-IN-5

CAS: 2581114-83-0

BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) & Aβ production (IC50: 0.82 nM), enhances hERG inhibition & P-gp efflux.

Formula: C₁₈H₁₆F₅N₅O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 461.41

Ref: TM-T10453