CAS 25812-30-0
:gemfibrozil
Description:
Gemfibrozil is a medication primarily used to lower lipid levels in patients with hyperlipidemia, particularly to reduce triglycerides and increase high-density lipoprotein (HDL) cholesterol. It belongs to the class of drugs known as fibrates and works by activating peroxisome proliferator-activated receptor alpha (PPARα), which enhances the oxidation of fatty acids and decreases the production of triglycerides in the liver. Chemically, gemfibrozil is characterized by its molecular formula, which includes carbon, hydrogen, and oxygen atoms, and it has a specific structural configuration that contributes to its pharmacological activity. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics involve extensive metabolism in the liver, primarily through glucuronidation, and it has a relatively long half-life, allowing for twice-daily dosing. Common side effects may include gastrointestinal disturbances, and it is contraindicated in patients with severe liver or kidney disease. As with any medication, monitoring lipid levels and potential drug interactions is essential during treatment.
Formula:C15H22O3
InChI:InChI=1/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
InChI key:InChIKey=HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES:O(CCCC(C(O)=O)(C)C)C1=C(C)C=CC(C)=C1
Synonyms:- 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid
- 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
- 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure
- 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
- 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
- 5-[(2,5-Dimethylphenyl)oxy]-2,2-dimethylpentanoic acid
- Apo-Gemfibrozil
- Ausgem
- Bolutol
- Brn 1881200
- Brozil
- Ccris 318
- Cholespid
- Ci 719
- Clearol
- Decrelip
- Elmogan
- Fetinor
- Fibratol
- Fibrocit
- Gem-S
- Gemd
- Gemfibril
- Gemfibromax
- Gemfibrozil [USAN:INN:BAN]
- Gemfibrozilo
- Gemfibrozilo [INN-Spanish]
- Gemfibrozilum
- Gemfibrozilum [INN-Latin]
- Gemlipid
- Gemnpid
- Genlip
- Gevilon
- Gevilon Uno
- Gozid
- Hidil
- Hipolixan
- Hsdb 7735
- Innogen
- Ipolipid
- Jezil
- Lanaterom
- Lifibron
- Lipazil
- Lipigem
- Lipira
- Lipizyl
- Lipur
- Litarek
- Lopid
- Lopizid
- Low-Lip
- Micolip
- Normolip
- Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
- Pilder
- Polyxit
- Progemzal
- Reducel
- Regulip
- Renabrazin
- Sinelip
- Synbrozil
- Taborcil
- Tentroc
- Trialmin
- Trialmin 900
- Unii-Q8X02027X3
- Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-
- WL-Gemfibrozil
- Gemfibrozil
- 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYLPENTANOICACID(GEMFIBROZIL)
- GEMFIBROZIL,USP
- 2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID
- 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoicaci
- 5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID
- Lipozid
- 2,2-dimethyl-5-(2,5-xylyloxy)-valericaci
- 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
- Gemcitabine intermediates
- 5-(2,5-Dimethylphenoxy)-2,2-DimethylpentamoicAcid
- 2,2-Dimethyl-5-(2,5-Dimethylphenoxy)Valeric
- CI-7
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 19 products.
Gemfibrozil
CAS:Formula:C15H22O3Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:250.34GEMFIBROZIL FOR SYSTEM SUITABILITY CRS
CAS:<p>GEMFIBROZIL FOR SYSTEM SUITABILITY CRS</p>Formula:C15H22O3Molecular weight:250.3334GEMFIBROZIL CRS
CAS:<p>GEMFIBROZIL CRS</p>Formula:C15H22O3Color and Shape:Waxy. Crystalline Powder. White. Powder.Molecular weight:250.3334Gemfibrozil
CAS:GemfibrozilFormula:C15H22O3Purity:99.9%Color and Shape:White SolidMolecular weight:250.15689Gemfibrozil
CAS:Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or includedFormula:C15H22O3Color and Shape:Off-White White PowderMolecular weight:250.33Gemfibrozil
CAS:<p>Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.</p>Formula:C15H22O3Purity:99.53% - 99.88%Color and Shape:Crystals From Hexane SolidMolecular weight:250.335-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS:Formula:C15H22O3Purity:98%Color and Shape:SolidMolecular weight:250.3334Gemfibrozil
CAS:Formula:C15H22O3Purity:≥ 98.0% (anhydrous basis)Color and Shape:White crystalline powderMolecular weight:250.33Gemfibrozil 100 µg/mL in Acetonitrile
CAS:Formula:C15H22O3Color and Shape:Single SolutionMolecular weight:250.33Gemfibrozil
CAS:Controlled Product<p>Applications A serum lipid regulating agent used as an antihyperlipoproteinemic.This compound is a contaminant of emerging concern (CECs).<br>References Kissebach, A.H., et al.: Atherosclerosis, 24, 199 (1976), Lewis, J.E., et al.: Pract. Cardiol., 9, 99 (1983), Rubins, H.B., et al.: N. Engl. J. Med., 341, 410 (1999)<br></p>Formula:C15H22O3Color and Shape:NeatMolecular weight:250.33Gemfibrozil
CAS:<p>Gemfibrozil is a chemical inhibitor that inhibits the response element to the transcription factor PPAR-α. It has been shown to decrease cardiac effects such as increased heart rate, stroke volume, and cardiac output. Gemfibrozil has been used for wastewater treatment and has been found to be an analytical method for determining the concentration of other drugs in urine. The ecological effects of gemfibrozil are not well understood, but it is known that it can cause adverse effects on locomotor activity in animals. Gemfibrozil is a potent inducer of liver enzymes and may interact with other drugs by increasing their concentration time curve. This drug also has oral hypoglycemic properties, which lowers the blood glucose level by stimulating insulin production.</p>Formula:C15H22O3Purity:Min. 95%Molecular weight:250.33 g/mol5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS:Formula:C15H22O3Purity:98%Color and Shape:Crystalline PowderMolecular weight:250.338
