CAS 25952-53-8

1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride

Description:

1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride, commonly referred to as EDC, is a water-soluble carbodiimide used primarily as a coupling agent in peptide synthesis and other applications involving the formation of amide bonds. It facilitates the activation of carboxylic acids, allowing them to react with amines to form stable amide linkages. EDC is characterized by its ability to promote reactions under mild conditions, making it suitable for sensitive biomolecules. The hydrochloride salt form enhances its solubility in aqueous solutions, which is advantageous for biological applications. EDC is typically handled with care, as it can be a skin and respiratory irritant. Its reactivity is influenced by the presence of other functional groups in the reaction mixture, and it is often used in conjunction with other reagents to improve coupling efficiency. Overall, EDC is a valuable tool in organic and medicinal chemistry, particularly in the synthesis of peptides and other amide-containing compounds.

Formula: C₈H₁₇N₃·ClH

InChI: InChI=1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key: InChIKey=FPQQSJJWHUJYPU-UHFFFAOYSA-N

SMILES: C(N=C=NCC)CCN(C)C.Cl

Synonyms:

• (3-Dimethylaminopropyl)Ethyl-Carbodiimidmonohydrochloride
• 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride
• 1,3-Propanediamine, N3-(ethylcarbonimidoyl)-N1,N1-dimethyl-, hydrochloride (1:1)
• 1,3-Propanediamine, N³-(ethylcarbonimidoyl)-N¹,N¹-dimethyl-, hydrochloride (1:1)
• 1-(3-Dimethyl-aminopropyl)-3-ethylcarbodiimide hydrochloride
• 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide monohydrochloride
• 1-Ethy-3-(3'-dimethylaminopropyl) carbodiimide hydrochloride
• 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide monohydrochloride
• 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide Hydrochloride
• 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrchloride
• 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride
• 1-Ethyl-3-(dimethylaminopropyl)carbodiimide hydrochloride
• 1-[3-(Dimethylamino)Propyl]-3-Ethylcarbodiimide Hydrochloride
• 1-[3-Dimethylamino propyl]-3-ethyl carbodiimide Hcl
• 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine,hydrochloride
• 3-Propanediamine,N'-(Ethylcarbonimidoyl)-N,N-Dimethyl-Monohydrochloride
• 3-[3-(Dimethylamino)propyl]-1-ethylcarbodiimide hydrochloride
• 3-[cyano(ethyl)amino]-N,N-dimethylpropan-1-aminium chloride
• 3-ethylazo-N,N-dimethyl-propan-1-amine hydrochloride
• Carbodiimide, [3-(dimethylamino)propyl]ethyl-, monohydrochloride
• EDAC,HCl
• EDC
• EDC (WSC-HCl)
• EDC (coupling agent)
• EDC・HCl
• Edap
• Edc.Hcl
• Edci
• N'-(Ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine, monochlorhydrate
• N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminmonohydrochlorid
• N'-(ethylcarboneimidoyl)-N,N-dimethylpropane-1,3-diamine, monochlorhydrate
• N'-(ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride
• N'-(etilcarbonoimidoil)-N,N-dimetilpropano-1,3-diamina, monoclorhidrato
• N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride
• N-Ethyl-N-(3-dimethylaminopropyl)carbodiimide hydrochloride
• N-[(Ethylimino)methylene]-N′,N′-dimethylpropane-1,3-diamine hydrochloride
• N-[3-(Dimethylamino)propyl]-N¹-ethylcarbodiimide hydrochloride
• N¹-((Ethylimino)methylene)-N³,N³-dimethylpropane-1,3-diamine hydrochloride
• WSC

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride [Coupling Agent for Peptides Synthesis]

CAS: 25952-53-8

Formula: C₈H₁₇N₃·HCl

Purity: >98.0%(T)

Color and Shape: White powder to crystal

Molecular weight: 191.70

Ref: 3B-D1601

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%

CAS: 25952-53-8

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biom

Formula: C₈H₁₈ClN₃

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 191.70

Ref: 02-A10807

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride

CAS: 25952-53-8

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride

Formula: C₈H₁₇N₃·ClH

Purity: 99%

Color and Shape: Off-white Solid-Crystals

Molecular weight: 191.70162

Ref: 54-BIE1308

N-[3-(Dimethylamino)prop-1-yl]-N'-ethylcarbodiimide hydrochloride

CAS: 25952-53-8

N-[3-(Dimethylamino)prop-1-yl]-N'-ethylcarbodiimide hydrochloride

Formula: C₈H₁₇N₃·ClH

Purity: ≥95%

Color and Shape: Off-white Solid-Crystals

Molecular weight: 191.70162

Ref: 54-OR5163

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, HCl

CAS: 25952-53-8

Formula: C₈H₁₈ClN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.7016

Ref: IN-DA0033GC

EDC hydrochloride

CAS: 25952-53-8

EDC hydrochloride (EDC-hcl Crosslinker) is a water-soluble carbodiimide compound. EDC hydrochloride forms peptide bonds. High-Quality, Low-Cost!

Formula: C₈H₁₈ClN₃

Purity: 99.59% - 99.99%

Color and Shape: White Solid

Molecular weight: 191.7

Ref: TM-T19947

EDC hydrochloride

CAS: 25952-53-8

Formula: C₈H₁₇N₃·HCl

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 191.70

Ref: 7W-GP0849

EDC hydrochloride

CAS: 25952-53-8

Formula: C₈H₁₈ClN₃

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 191.7

Ref: 10-F024810

EDC·HCl

CAS: 25952-53-8

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

Formula: C₈H₁₈ClN₃

Purity: 99%

Molecular weight: 191.7

Ref: IN-DG19757

EDC HCl (Mirabegron EP Impurity I HCl)

CAS: 25952-53-8

Formula: C₈H₁₇N₃·HCl

Molecular weight: 155.25 36.46

Ref: 4Z-E-154001

N-Ethyl-N’-(3-dimethylaminopropyl)carbodimide Hydrochloride

CAS: 25952-53-8

Applications An enzyme inhibitor.

Formula: C₈H₁₈ClN₃

Color and Shape: Neat

Molecular weight: 191.7

Ref: TR-E916635

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

CAS: 25952-53-8

Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptide synthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports.

Formula: C₈H₁₈ClN₃

Molecular weight: 191.7 g/mol

Ref: 3D-Z-1027

EDC HCl

CAS: 25952-53-8

Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptide synthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports.

Formula: C₈H₁₈ClN₃

Purity: (Argentometric Titration) Min. 98%

Color and Shape: White Powder

Molecular weight: 191.7 g/mol

Ref: 3D-FD05800

1-(3-Dimethylaminopropyl)-3-Ethyl Carbodiimide Hydrochloride (EDC.HCl, EDAC.HCl) extrapure, 99%

CAS: 25952-53-8

Formula: C₈H₁₇N₃HCI

Purity: min. 99% (on anhydrous basis)

Color and Shape: White to off white, Crystalline powder

Molecular weight: 191.70

Ref: SR-49235

N-Ethyl-N’-(3-dimethylaminopropyl)-carbodiimide · HCl

CAS: 25952-53-8

A water-soluble coupling reagent for solution synthesis. WSCD has also been employed in SPPS in aqueous systems.

Formula: C₈H₁₇N₃·HCl

Color and Shape: White

Molecular weight: 191.7

Ref: 01-4031236