CAS 25953-19-9
:Cefazolin
Description:
Cefazolin is a first-generation cephalosporin antibiotic, primarily used for the treatment of bacterial infections. It is effective against a variety of gram-positive bacteria and some gram-negative organisms. Cefazolin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection, as it is not well absorbed from the gastrointestinal tract. Its chemical structure includes a beta-lactam ring, which is essential for its antibacterial activity. Cefazolin is often used in surgical prophylaxis and for treating infections such as skin and soft tissue infections, urinary tract infections, and respiratory tract infections. It is generally well-tolerated, but potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood clotting. As with all antibiotics, it is crucial to use cefazolin judiciously to prevent the development of antibiotic resistance. Its CAS number, 25953-19-9, uniquely identifies this compound in chemical databases.
Formula:C14H14N8O4S3
InChI:InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
InChI key:InChIKey=MLYYVTUWGNIJIB-BXKDBHETSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(CN3C=NN=N3)=O)C2=O)(SCC1CSC=4SC(C)=NN4)[H]
Synonyms:- (6R,7R)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R-trans)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol- 1-ylacetyl)amino]-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-, (6R-trans)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-, (6R,7R)-
- 7-(1-(1H)-Tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-Δ3-cephem-4-carboxylic acid
- 7-(1-(1H)-Tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 7-(1H-Tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid
- 7-[1-(1H)-tetrazolylacetoamido]-3-[2-(5-methyl-1,3,4-thiadiazolyl)-thiomethyl]-Δ-3-cephem-4-carboxylic acid
- CEZ
- Cefamedin
- Cefamezin
- Cefaprim
- Cefazolin,sodium salt
- Cefazolina
- Cefazoline
- Cephamezine
- Cephazolin
- Cephazolin,sodium salt
- Cephazoline
- Elzogram
- Sefazol
- Zinol
- CEFAZOLIN
- 7-(1-(1h-)-tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]d
- diazol-2-yl)thio)methyl)-8-oxo-7-(2-(1h-tetrazol-1-yl)acetamido)-
- CEFAZOLIN ACID
- diazol-2-yl)thio)methyl)-8-oxo-7-((1h-tetra
- diazol-2-yl)thio)methyl)-8-oxo-7-(2-(1h-t-
- elta3-cephem-4-carboxylicacid
- (6r-trans)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[(1h-tetr
- CefazoilnV
- Cefazoline sodium sterile IP/Bp
- azol-1-yl)acetyl]-amino]-5-thia-1-azabicylo
- See more synonyms
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Found 16 products.
Cefazolin
CAS:Antibiotics nesoiFormula:C14H14N8O4S3Color and Shape:White Off-White Crystalline PowderMolecular weight:454.03001Cefazolin Impurity 45
CAS:Formula:C13H14N6O6SColor and Shape:White To Off-White SolidMolecular weight:382.35Cefazolin
CAS:Formula:C14H14N8O4S3Purity:≥ 98.0% (dry basis)Color and Shape:White to off-white powderMolecular weight:454.51Cefazolin 1000 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C14H14N8O4S3Color and Shape:Single SolutionMolecular weight:454.51Cefazolin
CAS:Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.Formula:C14H14N8O4S3Purity:99.51%Color and Shape:Needles From Aqueous Acetone SolidMolecular weight:454.51Cefazolin
CAS:Controlled ProductApplications Cefazolin is an antibacterial compound derived from 7-amino-cephalosporanic acid.
References Kozatani, et al.: Chem. Pharm. Bull., 20, 1105 (1972), Birkhead, H.A., et al.: J. Infect. Dis., 128, 379 (1973), Zappala, A.E., et al.: Anal. Profiles Drug Subs., 4, 1 (1975),Formula:C14H14N8O4S3Color and Shape:NeatMolecular weight:454.51Cefazolin
CAS:Cefazolin is a broad-spectrum antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It is an effective cephalosporin antibiotic against both aerobic and anaerobic bacteria. Cefazolin is used in clinical isolates to inhibit the growth of methicillin-resistant staphylococcus, resistant microorganisms, and systemic inflammation. Some studies has shown good results to inhibit tumor necrosis factor-α (TNFα) production in cell culture.Formula:C14H14N8O4S3Purity:Min. 95%Molecular weight:454.51 g/mol
