CAS 259793-96-9
:Favipiravir
Description:
Favipiravir, with the CAS number 259793-96-9, is an antiviral medication primarily used to treat influenza and has been investigated for its efficacy against other viral infections, including COVID-19. It is a pyrazinecarboxamide derivative and functions as a prodrug, which is converted in the body to its active form that inhibits viral RNA polymerase, thereby disrupting viral replication. Favipiravir is characterized by its relatively low molecular weight and moderate solubility in water, which facilitates its administration in various formulations. The compound exhibits a broad spectrum of antiviral activity, particularly against RNA viruses. Its pharmacokinetics include oral bioavailability, and it is metabolized primarily in the liver. Favipiravir's safety profile includes potential side effects such as elevated liver enzymes and gastrointestinal disturbances, necessitating monitoring during treatment. Overall, Favipiravir represents a significant therapeutic option in the antiviral arsenal, especially in the context of emerging viral outbreaks.
Formula:C5H4FN3O2
InChI:InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
InChI key:InChIKey=ZCGNOVWYSGBHAU-UHFFFAOYSA-N
SMILES:C(N)(=O)C=1C(=O)NC=C(F)N1
Synonyms:- 2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-
- 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
- 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide
- 6-Fluoro-3-Oxo-3,4-Dihydropyrazine-2-Carboxamide
- 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide
- Avigan
- FabiFlu
- Favilavir
- Favipiravir
- Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-
- Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-(9CI)
- T 705 (pharmaceutical)
- See more synonyms
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Favipiravir
CAS:Formula:C5H4FN3O2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:157.106-Fluoro-3-hydroxy-2-pyrazinecarboxamide
CAS:Formula:C5H4FN3O2Purity:99%Color and Shape:SolidMolecular weight:157.1026Favipiravir
CAS:Controlled ProductApplications Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. It is a COVID19-related research product.
References Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)Formula:C5H4FN3O2Color and Shape:NeatMolecular weight:157.10Favipiravir
CAS:6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamideFormula:C5H4FN3O2Purity:99%Molecular weight:157.1Favipiravir
CAS:Formula:C5H4FN3O2Purity:≥ 98.0%Color and Shape:White to off-white or beige powderMolecular weight:157.10Favipiravir (T-705)
CAS:Favipiravir (T-705)
Formula:C5H4FN3O2Purity:98%Color and Shape: pale yellow solidMolecular weight:157.10g/molFavipiravir
CAS:Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Formula:C5H4FN3O2Purity:97.32% - 99.90%Color and Shape:SolidMolecular weight:157.10266-Fluoro-3-hydroxypyrazine-2-carboxamide
CAS:6-Fluoro-3-hydroxypyrazine-2-carboxamide is a potent RNA polymerase inhibitor, active against both RNA viruses in vitro and in vivo. A four-step approach to the synthesis of 6-Fluoro-3-hydroxypyrazine-2-carboxamide was reported in 2014. 6-Fluoro-3-hydroxypyrazine-2-carboxamide is commercialized and has recently been suggested for the treatment of mild cases of COVID-19.Formula:C5H4FN3O2Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:157.1 g/mol
