CAS 260415-63-2

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]-

Description:

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]- is a complex organic compound characterized by its fused pyrido and pyrimidine rings, which contribute to its heterocyclic nature. The presence of a dichlorophenyl group and a methylthio-substituted phenyl group indicates significant functional diversity, potentially influencing its biological activity and solubility. This compound is likely to exhibit properties typical of heterocycles, such as varied reactivity and potential for forming hydrogen bonds due to the nitrogen atoms in its structure. Its molecular framework suggests potential applications in pharmaceuticals, particularly in the development of therapeutic agents, given the structural motifs often associated with bioactive compounds. The specific arrangement of substituents can affect its pharmacokinetics and pharmacodynamics, making it a candidate for further investigation in medicinal chemistry. As with many organic compounds, its stability, solubility, and reactivity will depend on environmental conditions and the presence of other chemical species.

Formula: C₂₁H₁₆Cl₂N₄OS

Synonyms:

• Pd 173955
• 6-(2,6-Dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]-

CAS: 260415-63-2

Formula: C₂₁H₁₆Cl₂N₄OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 443.3489

Ref: IN-DA002RGX

PD173955

CAS: 260415-63-2

PD173955

Purity: ≥98%

Molecular weight: 443.35g/mol

Ref: 54-BUP08374

PD-173955

CAS: 260415-63-2

Ref: 7W-GW0583

PD173955

CAS: 260415-63-2

PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and

Formula: C₂₁H₁₆Cl₂N₄OS

Purity: 98.52% - 98.99%

Color and Shape: Solid

Molecular weight: 443.35

Ref: TM-T3063

PD173955

CAS: 260415-63-2

PD173955 is a potent, selective and orally bioavailable inhibitor of the Abl kinase that has been shown to inhibit tumor growth in mouse models. PD173955 binds to the ATP-binding site of Abl kinase and blocks ATP binding, preventing the formation of an enzyme-substrate complex. PD173955 also inhibits colony-stimulating factor activity, which may be due to its inhibition of bcr-abl kinase activity.

Formula: C₂₁H₁₆Cl₂N₄OS

Purity: Min. 95%

Molecular weight: 443.35 g/mol

Ref: 3D-KKA41563