CAS 26049-94-5

(3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone

Description:

(3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone, with CAS number 26049-94-5, is a chemical compound that features a complex structure characterized by the presence of a benzyloxycarbonyl group, a chloro substituent, and a ketone functional group. This compound is typically classified as an amino ketone, which indicates the presence of both an amine and a carbonyl group in its structure. The stereochemistry is specified as (3S), indicating that the configuration at the chiral center is S (sinister). The presence of the phenyl group contributes to its aromatic characteristics, while the chloro group introduces reactivity that can be exploited in various chemical reactions. This compound may be of interest in synthetic organic chemistry, particularly in the development of pharmaceuticals or as an intermediate in the synthesis of more complex molecules. Its solubility, stability, and reactivity would depend on the specific conditions and solvents used in its handling and application.

Formula: C₁₈H₁₈ClNO₃

InChI: InChI=1/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)

InChI key: InChIKey=OYHLRJGDELITAF-INIZCTEOSA-N

SMILES: [C@@H](CC1=CC=CC=C1)(NC(OCC2=CC=CC=C2)=O)C(CCl)=O

Synonyms:

• (3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone
• (S)-benzyl [1-benzyl-3-chloro-2-oxopropyl]carbamate
• Benzyl (4-Chloro-3-Oxo-1-Phenylbutan-2-Yl)Carbamate
• Carbamic acid, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester
• Carbamic acid, [(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester
• Carbamic acid, [3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, (S)-
• Carbamic acid, [α-(chloroacetyl)phenethyl]-, benzyl ester, <span class="text-smallcaps">L</span>-
• NSC 251810
• Zpck
• [N^α-(Benzyloxycarbonyl)phenylalanyl]chloromethane
• benzyl [(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate
• [Nα-(Benzyloxycarbonyl)phenylalanyl]chloromethane
• Carbamic acid, [α-(chloroacetyl)phenethyl]-, benzyl ester, L-
• (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamic
• N-CBZ-L-PHENYLALANYL-CHLOROMETHYLKETONE
• (S)-Penzyl [1-benzyl-3-chloro-2-oxopropyl]carbamate.
• ZPCK, N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone
• Z-L-PHENYLALANINE-CHLOROMETHYLKETONE
• Z-PHE-CH2CL
• N-CBZ-L-PHENYLETHYL CHLOROMETHYL KETONE
• Z-PHE-CHLOROMETHYLKETONE
• Z-L-Phe-CMK
• Z-L-Phe-Chloromethane
• (S)-Benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate
• N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketoneN-CBZ-L-Phenylalanylchloromethyl ketone
• (3S)-1-Chloro-3-(benzyloxycarbonylamino)-4-phenyl-2-butanone
• Z-L-Phe chloromethyl ketone 98%
• [(S)-α-(Chloroacetyl)phenethyl]carbamic acid benzyl ester
• N-ALPHA-CARBOBENZOXY-L-PHENYLALANINE CHLOROMETHYLKETONE
• z-l-phe chloromethyl ketone
• N-CARBOBENZYLOXY-L-PHENYLALANYL CHLOROMETHYL KETONE
• N-CBZ-L-PHENYLALANINE CHLOROMETHYL*KETON E
• Z-PHE-CMK
• [(S)-1-Benzyl-3-chloro-2-oxopropyl]carbamic acid benzyl ester
• SL-01
• carbamicacid,[3-chloro-2-oxo-1-(phenylmethyl)propyl]-,phenylmethylester,(s

Z-Phe-chloromethylketone

CAS: 26049-94-5

Z-Phe-CMK (ZPCK), an active site-specific inhibitor for the study of enzymes. ZPCK has been shown to inhibit both peptidase and esterase activities of carboxypeptidase Y from baker’s yeast.

Formula: C₁₈H₁₈ClNO₃

Purity: > 98%

Color and Shape: White

Molecular weight: 331.8

Ref: 01-4007012

Carbamic acid, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester

CAS: 26049-94-5

Formula: C₁₈H₁₈ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 331.7934

Ref: IN-DA002RID

SL-01

CAS: 26049-94-5

SL-01, an oral gemcitabine derivative, potently induces apoptosis to hinder breast cancer more effectively than gemcitabine.

Formula: C₁₈H₁₈ClNO₃

Purity: 98%

Color and Shape: White Powder

Molecular weight: 331.79

Ref: TM-T19779

Z-L-Phe chloromethyl ketone

CAS: 26049-94-5

Ref: 7W-GM3347

SL 01

Controlled Product

CAS: 26049-94-5

Applications SL 01 is a p53/mdm2 inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhao, C., et. al.: Cancer Chemother. Pharmacol., 71, 1541 (2013)

Formula: C₁₈H₁₈ClNO₃

Color and Shape: Neat

Molecular weight: 331.79

Ref: TR-S560010