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CAS 26159-34-2

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Naproxen sodium

Description:
Naproxen sodium is the sodium salt form of naproxen, a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, inflammation, and fever. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral and injectable formulations. Naproxen sodium has a relatively long half-life, allowing for twice-daily dosing in therapeutic applications. It is often used to treat conditions such as arthritis, menstrual pain, and other musculoskeletal disorders. While generally well-tolerated, it can cause side effects, including gastrointestinal discomfort, cardiovascular risks, and potential kidney effects, particularly with long-term use. As with all medications, it is essential to use naproxen sodium under medical supervision to mitigate risks and ensure appropriate dosing.
Formula:C14H14O3·Na
InChI:InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/t9-;/m0./s1
InChI key:InChIKey=CNQOEXOJUIMDHW-FVGYRXGTSA-N
SMILES:[C@H](C(O)=O)(C)C1=CC2=C(C=C(OC)C=C2)C=C1.[Na]
Synonyms:
  • (+)-(S)-Naproxen sodium salt
  • (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt
  • 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, sodium salt (1:1), (αS)-
  • 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, sodium salt, (S)-
  • 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, sodium salt, (αS)-
  • 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, sodium salt, <span class="text-smallcaps">L</span>-(-)-
  • 6-Methoxy-Alpha-Methyl-,Sodiumsalt,(S)-2-Naphthaleneaceticaci
  • 6-Methoxy-Alpha-Methyl-,Sodiumsalt,L-(-)-2-Naphthaleneaceticacid
  • Aflaxen
  • Agilxen
  • See more synonyms
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