CAS 2622-26-6
:Periciazine
Description:
Periciazine is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the class of phenothiazines, which are characterized by their ability to block dopamine receptors in the brain, thereby helping to alleviate symptoms such as hallucinations and delusions. Periciazine exhibits a moderate sedative effect and can also be used to manage anxiety and agitation. The compound is typically administered in oral form, and its pharmacokinetics involve metabolism in the liver, with excretion primarily through urine. Common side effects may include sedation, dry mouth, and potential extrapyramidal symptoms, which are movement disorders associated with antipsychotic medications. Due to its effects on the central nervous system, caution is advised when prescribing periciazine, especially in patients with a history of seizures or those taking other CNS depressants. Overall, periciazine is a valuable therapeutic option in the management of severe psychiatric conditions, although it requires careful monitoring for side effects and interactions with other medications.
Formula:C21H23N3OS
InChI:InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
InChI key:InChIKey=LUALIOATIOESLM-UHFFFAOYSA-N
SMILES:C(CCN1CCC(O)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C#N)C3
Synonyms:- 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile
- 10-[3-(4-Hydroxypiperidino)propyl]phenothiazine-2-carbonitrile
- 2-Cyano-10-[3'-(4''-hydroxypiperidino)propyl]phenothiazine
- 2-Cyano-10-[3-(4-hydroxy-1-piperidyl)propyl]phenothiazine
- Aolept
- Bayer 1409
- Fi 6145
- Nelactil
- Nemactil
- Neulactil
- Neuleptil
- Periciazin
- Periciazina
- Periciazine
- Periciazinum
- Pericyazine
- Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxypiperidino)propyl]-
- Properciazine
- Propericiazine
- Propericyazine
- Rp 8909
- Skf 20716
- 10H-Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxy-1-piperidinyl)propyl]-
- See more synonyms
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Pericyazine
CAS:Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist.Formula:C21H23N3OSPurity:99.61%Color and Shape:SolidMolecular weight:365.492Pericyazine (Propericiazine)
CAS:Formula:C21H23N3OSColor and Shape:Yellow SolidMolecular weight:365.5010-(3-(4-Hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile , Pericyazine
CAS:Formula:C21H23N3OSPurity:97%Color and Shape:SolidMolecular weight:365.4918Pericyazine
CAS:Controlled ProductApplications Psychotherapeutic phenothiazine. Antipsychotic.
References Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Kaye, J., et al.: Br. J. Clin. Pharmacol., 56, 569 (2003), Tschoner, A., et al.: Pharmacopsychiatry, 42, 29 (2009),Formula:C21H23N3OSColor and Shape:NeatMolecular weight:365.49Periciazine
CAS:Controlled ProductPericiazine is a pharmacological agent that acts as an antagonist at the CB2 receptor. It has been shown to have a matrix effect in the serum of prolactin levels, but does not affect other hormones such as corticosterone and estrogen. Periciazine has been shown to be toxic at high doses, but is less toxic and causes low mortality rates when administered at low doses. This drug also has a protein target: human serum albumin. The cb2 receptor is found in human serum and can be detected using LC-MS/MS methods, with high values indicating the presence of periciazine in blood samples.Formula:C21H23N3OSPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:365.49 g/mol
