CAS 264218-23-7: SB 415286

Description: SB 415286, with the CAS number 264218-23-7, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth, division, and apoptosis. The compound's structure typically features a core that allows for specific interactions with its target kinases, enhancing its selectivity and efficacy. In preclinical studies, SB 415286 has shown promise in modulating signaling pathways associated with cancer and other diseases, making it a candidate for further investigation in drug development. Its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME), are essential for determining its suitability for clinical use. As with many investigational compounds, ongoing research aims to elucidate its full therapeutic potential and safety profile.

Formula: C₁₆H₁₀ClN₃O₅

InChI: InChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)

InChI key: InChIKey=PQCXVIPXISBFPN-UHFFFAOYSA-N

SMILES: O=C1NC(=O)C(C=2C=CC=CC2N(=O)=O)=C1NC3=CC=C(O)C(Cl)=C3

Synonyms:

• 1H-Pyrrole-2,5-dione, 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-
• Sb 415286
• 3-[(3-Chloro-4-hydroxyphenyl)-amino]-4-(2-nitrophenyl)-1H-pyrrol-2,5-dione
• 3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
• 3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione

1H-Pyrrole-2,5-dione, 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-

CAS: 264218-23-7

• Formula: C₁₆H₁₀ClN₃O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 359.7207

SB 415286

CAS: 264218-23-7

• Formula: C₁₆H₁₀N₃O₅Cl
• Molecular weight: 359.72

SB 415286

CAS: 264218-23-7

SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally …

• Formula: C₁₆H₁₀ClN₃O₅
• Purity: 99.55%
• Color and Shape: Solid
• Molecular weight: 359.72

SB-415286

CAS: 264218-23-7

SB-415286 is a small molecule inhibitor of GSK-3β. It prevents phosphorylation of the substrate by …

• Formula: C₁₆H₁₀ClN₃O₅
• Purity: Min. 95%
• Molecular weight: 359.72 g/mol