gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
Found 110 products for "gsk-3".
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9-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purity:99.28% - 99.32%Color and Shape:SolidMolecular weight:404.3474Indazole
CAS:Indazole, a heterocyclic compound, offers diverse biological activities.Formula:C7H6N2Purity:99.59% - 99.85%Color and Shape:White SolidMolecular weight:118.1359Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purity:99.4% - 99.95%Color and Shape:White SolidMolecular weight:512.33BRD0705
CAS:BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Formula:C20H23N3OPurity:99.01%Color and Shape:SolidMolecular weight:321.4161CHIR-98023
CAS:CHIR-98023 is a bio-active chemical.Formula:C20H16Cl2N8O2Color and Shape:SolidMolecular weight:471.30PROTAC GSK-3β Degrader-1
PROTACGSK-3β Degrader-1 (compound 1) is a degrader targeting GSK-3β with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3β inhibitor), a PEG linker, and CRBN (E3 ligase ligand). It reduces neurotoxicity induced by Aβ25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.Formula:C43H42Cl2N6O9Color and Shape:SolidMolecular weight:856.23903GSK3-IN-1
CAS:GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.Formula:C14H10ClN3OSPurity:99.99%Color and Shape:SolidMolecular weight:303.767GSK-3β inhibitor 21
GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.Color and Shape:Odour SolidPhospho-Glycogen Synthase Peptide-2(substrate)
CAS:Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Formula:C123H191N40O48PColor and Shape:SolidMolecular weight:3029.087GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formula:C15H12N4O2SColor and Shape:SolidMolecular weight:312.35MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purity:99.64%Color and Shape:SolidMolecular weight:370.2GSK-3 Inhibitor 5
CAS:4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.Formula:C9H6BrNOPurity:99.9%Color and Shape:SolidMolecular weight:224.054GSK3β/mTOR modulator 1
GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.Formula:C19H28O5Color and Shape:SolidMolecular weight:336.19367FRATide
CAS:FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.Formula:C55H102N2O2Color and Shape:SolidMolecular weight:823.433GSK-3β/HDAC-IN-2
GSK-3β/HDAC-IN-2 is a potent inhibitor of GSK-3β (IC50 = 0.04 μM), HDAC2 (IC50 = 1.05 μM, Ki = 0.070 μM), and HDAC6 (IC50 = 1.52 μM, Ki = 0.017 μM). It effectively inhibits HDAC2 and HDAC6 activities and prevents the hyperphosphorylation of tau protein. GSK-3β/HDAC-IN-2 demonstrates neuroprotective properties without significant toxicity and is useful for Alzheimer's disease research.Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidGSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Formula:C18H15N5O3Color and Shape:SolidMolecular weight:349.352B-(SP)
CAS:Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)Formula:C71H123N26O29PPurity:98%Color and Shape:SolidMolecular weight:1835.87BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.Formula:C21H16N2O6Color and Shape:SolidMolecular weight:392.36GSK-3β inhibitor 1
CAS:GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurity:99.40%Color and Shape:SolidMolecular weight:222.24
