Description:PR-619, with the CAS number 2645-32-1, is a chemical compound known primarily as a proteasome inhibitor. It is characterized by its ability to interfere with the proteasome's function, which is crucial for protein degradation and regulation within cells. This inhibition can lead to the accumulation of proteins that regulate various cellular processes, including cell cycle progression and apoptosis. PR-619 has been studied for its potential therapeutic applications, particularly in cancer treatment, as it may enhance the efficacy of certain chemotherapeutic agents by disrupting the balance of protein turnover in cancer cells. Additionally, PR-619 is often utilized in research settings to investigate the role of the ubiquitin-proteasome pathway in various biological processes. Its solubility and stability in different solvents can vary, making it important to consider these factors when designing experiments. Overall, PR-619 serves as a valuable tool in both therapeutic and research contexts, contributing to our understanding of cellular mechanisms and potential treatment strategies.
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