CAS 2648641-36-3

Zotizalkib

CAS: 2648641-36-3

Zotizalkib

Purity: ≥98%

Molecular weight: 447.41g/mol

Ref: 54-BUP13835

TPX0131

CAS: 2648641-36-3

TPX0131 is a recombinant human anti-IL8 antibody. TPX0131 has been shown to inhibit IL8 induced neutrophil chemotaxis and to block the IL8 receptor. TPX0131 also blocks the activation of NF-κB, a transcription factor involved in inflammation, and inhibits IL8 induced expression of adhesion molecules on endothelial cells. The affinity of TPX0131 for IL8 is low (Kd=1.5 nM) and it has high purity (>98%).

Formula: C₂₁H₂₀F₃N₅O₃

Purity: Min. 95%

Molecular weight: 447.4 g/mol

Ref: 3D-FT181395

Zotizalkib

CAS: 2648641-36-3

TPX-0131: potent, selective, CNS-ready, oral ALK inhibitor (WT IC50: 1.4nM, G1202R/L1196M IC50: 0.3nM) with robust antitumor effects.

Formula: C₂₁H₂₀F₃N₅O₃

Purity: 98.7%

Color and Shape: Solid

Molecular weight: 447.41

Ref: TM-T9414