CAS 265651-18-1: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate

Description: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate, commonly referred to as HATU, is a coupling reagent widely used in peptide synthesis and other organic reactions. It is characterized by its ability to activate carboxylic acids for amide bond formation, facilitating the coupling of amino acids in peptide synthesis. The compound is typically a white to off-white solid and is soluble in polar organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). HATU is known for its efficiency and mild reaction conditions, which minimize side reactions and enhance yield. It is also favored for its stability under standard laboratory conditions, although it should be handled with care due to its reactivity and potential toxicity. The presence of the succinimidyl group allows for selective reactions with amines, making it a valuable tool in the synthesis of complex organic molecules. Proper storage in a cool, dry place away from moisture is recommended to maintain its integrity and effectiveness.

Formula: C₉H₁₆F₆N₃O₃P

InChI: InChI=1/C9H16N3O3.F6P/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;1-7(2,3,4,5)6/h5-6H2,1-4H3;/q+1;-1

Synonyms:

• Hstu
• O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium hexafluorophosphate
• N-{(dimethylamino)[(2,5-dioxopyrrolidin-1-yl)oxy]methylidene}-N-methylmethanaminium hexafluorophosphate

N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Hexafluorophosphate

CAS: 265651-18-1

• Formula: C₉H₁₆F₆N₃O₃P
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 359.21

O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%

CAS: 265651-18-1

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of …

• Formula: C₉H₁₆F₆N₃O₃P
• Purity: 98+%
• Molecular weight: 359.21

Methanaminium, (dimethylamino)[(2,5-dioxo-1-pyrrolidinyl)oxy]dimethyl-, hexafluorophosphate(1-) (1:1)

CAS: 265651-18-1

• Formula: C₉H₁₆F₆N₃O₃P
• Purity: 96%
• Color and Shape: Solid
• Molecular weight: 359.2058

O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 265651-18-1

• Purity: 98+%
• Color and Shape: Solid
• Molecular weight: 359.21g/mol

O-(N-Succinimidyl-1,1,3,3-tetramethyluronium hexafluorophosphate

CAS: 265651-18-1

• Purity: 99.5%
• Color and Shape: Solid
• Molecular weight: 359.2090148925781

HSTU

CAS: 265651-18-1

HSTU is an uronium salt used as an amide and ester coupling reagent, and to …

• Formula: C₉H₁₆F₆N₃O₃P
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 359.21 g/mol