CAS 2657-25-2

4'-Hydroxychalcone

Description:

4'-Hydroxychalcone is an organic compound belonging to the chalcone family, characterized by its structure that features a chalcone backbone with a hydroxyl group at the para position of the phenyl ring. It typically appears as a yellow to orange crystalline solid and is known for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. The compound is soluble in organic solvents such as ethanol and methanol but has limited solubility in water. Its molecular formula is C15H12O2, and it has a relatively low molecular weight. 4'-Hydroxychalcone is often studied for its role in various biochemical pathways and its potential applications in pharmaceuticals and nutraceuticals. Additionally, it serves as a precursor in the synthesis of other flavonoids and bioactive compounds. The compound's reactivity can be attributed to the presence of the hydroxyl group, which can participate in hydrogen bonding and influence its interaction with biological targets.

Formula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11,16H/b11-6+

InChI key: InChIKey=UAHGNXFYLAJDIN-UHFFFAOYSA-N

SMILES: C(C=CC1=CC=CC=C1)(=O)C2=CC=C(O)C=C2

Synonyms:

• (2E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one
• 1-(4-Hydroxyphenyl)-3-Phenylprop-2-En-1-One
• 1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one
• 1-(4-Hydroxyphenyl)-3-phenylpropenone
• 2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-
• 4-Hydroxyphenyl styryl ketone
• Benzylidene-(4-hydroxyacetophenone)
• Chalcone, 4′-hydroxy-
• NSC 242264
• p-Cinnamoylphenol
• 4′-Hydroxychalcone
• HYDROXYCHALCONE, 4'-
• 4'-Hydroxychalcone98%
• 2-BENZAL-4'-HYDROXYACETOPHENONE
• 1-(p-Hydroxyphenyl)-3-phenyl-2-propene-1-one
• 2-BENZYLIDENE-4'-HYDROXYACETOPHENONE
• HYDROXYCHALCONE, 4-(RG)
• 4'-Hydroxychalcone,97%

4'-Hydroxychalcone

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purity: >95.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 224.26

Ref: 3B-H0945

4'-Hydroxychalcone, 97%

CAS: 2657-25-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₅H₁₂O₂

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder, White to pale yellow

Molecular weight: 224.26

Ref: 02-A10838

2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 224.2546

Ref: IN-DA002TQO

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Purity: ≥98%

Molecular weight: 224.25g/mol

Ref: 54-BUP16799

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Formula: C₁₅H₁₂O₂

Purity: 98%

Color and Shape: Pale Yellow Powder

Molecular weight: 224.25g/mol

Ref: 54-OR2345

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity

Formula: C₁₅H₁₂O₂

Purity: 99.86% - 99.87%

Color and Shape: Yellow-Cream Powder

Molecular weight: 224.25

Ref: TM-T7917

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone is a compound that has shown to be an insulin resistance suppressant. It reduces the activity of recombinant cytochrome P450 enzymes and blocks hydroxy group metabolism, which leads to a decrease in ATP levels. This molecule also has biological properties as it can inhibit the expression of β-catenin and induce apoptosis in cancer cells. 4'-Hydroxychalcone has been found to inhibit the transfer mechanism of phosphatidylinositol 3-kinase (PTP1B) and is able to bind with the protein marker p62/SQSTM1.
4'-Hydroxychalcone is a potent inhibitor for PTP1B, which is a negative regulator for insulin signaling pathways. In addition, 4'-hydroxychalcone can bind with p62/SQSTM1, which is a marker for autophagy proteins. These properties have been shown to have anti-cancer effects on multiple cancer types including

Formula: C₁₅H₁₂O₂

Color and Shape: Powder

Molecular weight: 224.25 g/mol

Ref: 3D-FH36595

4′-Hydroxychalcone

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purity: 97%

Color and Shape: Solid, Yellow-cream powder

Molecular weight: 224.259

Ref: 10-F003112