CAS 2680616-96-8

Formula: C21H26F2N8

InChI: InChI=1S/C21H26F2N8/c1-13(2)31-17-8-18(25-10-15(17)11-26-31)28-19-7-16(14-3-5-24-9-14)27-20(29-19)30-6-4-21(22,23)12-30/h7-8,10-11,13-14,24H,3-6,9,12H2,1-2H3,(H,25,27,28,29)

InChI key: JKPAJCPZQIJPPS-UHFFFAOYSA-N

SMILES: CC(C)N1C2=CC(=NC=C2C=N1)NC3=NC(=NC(=C3)C4CCNC4)N5CCC(C5)(F)F

GNE-1858

CAS: 2680616-96-8

GNE-1858

Formula: C₂₁H₂₆F₂N₈

Purity: 99%

Molecular weight: 428.48

Ref: 54-BUP12822

GNE-1858

CAS: 2680616-96-8

Purity: 95%

Ref: IN-DA01X0VU

N-(2-(3,3-Difluoropyrrolidin-1-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-yl)-1-isopropyl-1H-pyrazolo[4,3-c]pyridin-6-amine

CAS: 2680616-96-8

N-(2-(3,3-Difluoropyrrolidin-1-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-yl)-1-isopropyl-1H-pyrazolo[4,3-c]pyridin-6-amine

Formula: C₂₁H₂₆F₂N₈

Purity: 95%

Molecular weight: 428.48

Ref: IN-DG01282160

GNE-1858

CAS: 2680616-96-8

GNE-1858 inhibits HPK1; IC50: 1.9 nM for wild-type, 1.9 nM (HPK1-TSEE), 4.5 nM (HPK1-SA).

Formula: C₂₁H₂₆F₂N₈

Purity: 99.36%

Color and Shape: Solid

Molecular weight: 428.4815

Ref: TM-T11438