CAS 26830-96-6

2-amino-4-methylbenzonitrile

Description:

2-Amino-4-methylbenzonitrile, with the CAS number 26830-96-6, is an organic compound characterized by the presence of an amino group (-NH2) and a nitrile group (-C≡N) attached to a benzene ring that also has a methyl group (-CH3) in the para position relative to the amino group. This compound is typically a solid at room temperature and is soluble in polar solvents due to the presence of the amino group, which can engage in hydrogen bonding. Its molecular structure contributes to its potential applications in pharmaceuticals and organic synthesis, where it may serve as an intermediate in the production of various chemical compounds. The presence of both the amino and nitrile functional groups allows for diverse reactivity, making it a valuable building block in organic chemistry. Additionally, its physical properties, such as melting point and boiling point, can vary based on purity and specific conditions. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₈H₈N₂

InChI: InChI=1/C8H8N2/c1-6-2-3-7(5-9)8(10)4-6/h2-4H,10H2,1H3

InChI key: InChIKey=LGNVAEIITHYWCG-UHFFFAOYSA-N

SMILES: C(#N)C1=C(N)C=C(C)C=C1

Synonyms:

• 2-Amino-p-toluonitrile
• 2-Cyano-5-methylaniline
• 4-Methyl-2-aminobenzonitrile
• 4-Methylanthranilonitrile
• Benzonitrile, 2-amino-4-methyl-
• p-Tolunitrile, 2-amino-
• 2-Amino-4-methylbenzonitrile

2-Amino-4-methylbenzonitrile, 98%

CAS: 26830-96-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₈N₂

Purity: 98%

Molecular weight: 132.17

Ref: 02-043260

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

Formula: C₈H₈N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 132.1625

Ref: IN-DA006TX6

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

Formula: C₈H₈N₂

Molecular weight: 132.17

Ref: 7W-GK5034

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

2-Amino-4-methylbenzonitrile

Formula: C₈H₈N₂

Purity: ≥95%

Color and Shape: pale yellow powder

Molecular weight: 132.16g/mol

Ref: 54-OR30201

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

Formula: C₈H₈N₂

Purity: >98.0%(GC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 132.17

Ref: 3B-A2448

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

2-Amino-4-methylbenzonitrile is a potent anticancer drug that inhibits the growth of cancer cells by targeting the active site of DNA polymerase β. It has been shown to have potent cytotoxicity against colorectal adenocarcinoma cells and cervical cancer cells, as well as inhibit cell proliferation and induce apoptosis in a number of other cancers. 2-Amino-4-methylbenzonitrile has been shown to be effective in nanomolar concentrations, which is important for potential use in combination therapies. This drug has also been studied using a variety of molecular profiling techniques to identify its mechanism of action. 2-Amino-4-methylbenzonitrile has been found to bind to the active site on DNA polymerase β and inhibit its activity, leading to the accumulation of errors during replication. This accumulation leads to the inhibition of protein synthesis and cell division, causing apoptosis.

Formula: C₈H₈N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 132.16 g/mol

Ref: 3D-FA70616

2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

Formula: C₈H₈N₂

Purity: 97%

Color and Shape: Solid, Yellow powder

Molecular weight: 132.166

Ref: 10-F064672