CAS 271-70-5

7H-pyrrolo[2,3-d]pyrimidine

Description:

7H-pyrrolo[2,3-d]pyrimidine is a heterocyclic organic compound characterized by a fused ring system that combines elements of pyrrole and pyrimidine. This compound features a bicyclic structure, where a pyrrole ring is fused to a pyrimidine ring, resulting in a nitrogen-rich framework. It typically exhibits a planar geometry, which can influence its electronic properties and reactivity. The presence of nitrogen atoms in the rings contributes to its potential as a ligand in coordination chemistry and its utility in medicinal chemistry, particularly in the development of pharmaceuticals. The compound may exhibit various physical properties, such as solubility in polar solvents, and can participate in diverse chemical reactions, including electrophilic substitutions and nucleophilic attacks. Its derivatives are of interest in research due to their biological activities, including potential anti-cancer and anti-inflammatory effects. Overall, 7H-pyrrolo[2,3-d]pyrimidine serves as a valuable scaffold in organic synthesis and drug discovery.

Formula: C₆H₅N₃

InChI: InChI=1/C6H5N3/c1-2-8-6-5(1)3-7-4-9-6/h1-4H,(H,7,8,9)

SMILES: c1cnc2c1cnc[nH]2

Synonyms:

• 3H-pyrrolo[2,3-d]pyrimidine
• Pyrrolo(2,3-d)pyrimidine
• 1H-Pyrrolo[2,3-d]pyrimidine
• Deazapurine

7-Deazapurine

CAS: 271-70-5

Formula: C₆H₅N₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 119.13

Ref: 3B-D4820

7H-pyrrolo[2,3-d]pyrimidine

CAS: 271-70-5

Formula: C₆H₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 119.1240

Ref: IN-DA0034EB

7H-Pyrrolo[2,3-d]pyrimidine

CAS: 271-70-5

7H-Pyrrolo[2,3-d]pyrimidine

Formula: C₆H₅N₃

Purity: 98%

Color and Shape: off-white to light yellow solid

Molecular weight: 119.12g/mol

Ref: 54-OR317000

7H-pyrrolo[2,3-d]pyrimidine

CAS: 271-70-5

Formula: C₆H₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 119.127

Ref: 10-F076158

7H-Pyrrolo[2,3d]pyrimidine

CAS: 271-70-5

7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has a

Formula: C₆H₅N₃

Purity: Min. 95%

Molecular weight: 119.12 g/mol

Ref: 3D-NP32608

7-Deazapurine

CAS: 271-70-5

Formula: C₆H₇N₃

Molecular weight: 121.14

Ref: ST-EA-CP-T23083