CAS 27220-47-9

Econazole

Description:

Econazole is an antifungal agent belonging to the imidazole class of compounds, primarily used in the treatment of various fungal infections. It exhibits broad-spectrum antifungal activity against dermatophytes, yeasts, and some molds by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately cell death. Econazole is typically formulated as a topical cream, lotion, or powder for localized application, making it effective for conditions such as athlete's foot, ringworm, and candidiasis. The substance is characterized by its relatively low solubility in water, which enhances its efficacy when applied to the skin. Additionally, it has a moderate lipophilicity, allowing for better penetration through the skin barrier. Econazole is generally well-tolerated, with minimal systemic absorption when used topically, although some local irritation may occur. Its chemical structure includes a 1H-imidazole ring, contributing to its pharmacological properties. Overall, Econazole is a valuable agent in dermatological antifungal therapy.

Formula: C₁₈H₁₅Cl₃N₂O

InChI: InChI=1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2

InChI key: InChIKey=LEZWWPYKPKIXLL-UHFFFAOYSA-N

SMILES: C(CN1C=CN=C1)(OCC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3

Synonyms:

• 1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole
• 1-[2,4-Dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]imidazole
• 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
• 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
• 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-
• Brn 0964150
• Ccris 9032
• Econazol
• Econazol [INN-Spanish]
• Econazolum
• Ecostatin
• Imidazole, 1,2,4-dichloro-beta-(p-chlorobenzyl)oxyphenethyl-
• Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-
• Imidazole, 1-[2,4-dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]-
• Nsc 187789
• Unii-6Z1Y2V4A7M

ECONAZOLE CRS

CAS: 27220-47-9

ECONAZOLE CRS

Formula: C₁₈H₁₅Cl₃N₂O

Color and Shape: White. Powder.

Molecular weight: 381.6835

Ref: 41-Y0001236

1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole

CAS: 27220-47-9

Formula: C₁₈H₁₅Cl₃N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 381.6835

Ref: IN-DA00I55M

Econazole

CAS: 27220-47-9

Econazole ((±)-Econazol) is an imidazole derivative that is commonly used as a topical antifungal agent.

Formula: C₁₈H₁₅Cl₃N₂O

Purity: 98.11% - 99.97%

Color and Shape: Solid

Molecular weight: 381.68

Ref: TM-T0444

Econazole

CAS: 27220-47-9

Econazole

Purity: ≥98%

Molecular weight: 381.68g/mol

Ref: 54-BUP18169

Miconazole EP Impurity B

CAS: 27220-47-9

Formula: C₁₈H₁₅Cl₃N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 381.68

Ref: 4Z-M-734

Econazole

CAS: 27220-47-9

Formula: C₁₈H₁₅Cl₃N₂O

Purity: (Titration) 99.0 - 101.0 % (dried basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 381.68

Ref: 7W-GA7153

Econazole

CAS: 27220-47-9

Formula: C₁₈H₁₅Cl₃N₂O

Color and Shape: Neat

Molecular weight: 381.68

Ref: 86-MM3432.00

1-(2-((4-Chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

CAS: 27220-47-9

Purity: 97.0%

Color and Shape: Liquid, No data available.

Molecular weight: 381.67999267578125

Ref: 10-F498377

Econazole

Controlled Product

CAS: 27220-47-9

Applications Econazole (cas# 27220-47-9) is a compound useful in organic synthesis.

Formula: C₁₈H₁₅Cl₃N₂O

Color and Shape: Neat

Molecular weight: 381.68

Ref: TR-E326003

Miconazole EP Impurity B

CAS: 27220-47-9

Formula: C₁₈H₁₅Cl₃N₂O

Molecular weight: 381.7

Ref: ST-EA-CP-M46002

Econazole

CAS: 27220-47-9

Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.

Formula: C₁₈H₁₅Cl₃N₂O

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 381.68 g/mol

Ref: 3D-FC33390

Econazole

CAS: 27220-47-9

Color and Shape: Neat

Ref: 61-FOR3432.00