CAS 27318-90-7

1,10-Phenanthroline-5,6-dione

Description:

1,10-Phenanthroline-5,6-dione, with the CAS number 27318-90-7, is an organic compound characterized by its unique structure, which includes a phenanthroline backbone with two carbonyl groups at the 5 and 6 positions. This compound typically appears as a yellow to orange solid and is known for its ability to chelate metal ions, making it useful in various analytical and coordination chemistry applications. It exhibits strong absorbance in the UV-Vis spectrum, which is often utilized in spectrophotometric analyses. The presence of the dione functional groups contributes to its reactivity, allowing it to participate in redox reactions. Additionally, 1,10-Phenanthroline-5,6-dione can serve as a ligand in the formation of metal complexes, which are of interest in catalysis and materials science. Its properties make it a valuable compound in research settings, particularly in studies involving transition metals and their interactions with organic ligands. Safety data should be consulted before handling, as with all chemical substances.

Formula: C₁₂H₆N₂O₂

InChI: InChI=1/C12H6N2O2/c15-11-7-3-1-5-13-9(7)10-8(12(11)16)4-2-6-14-10/h1-6H

SMILES: c1cc2c(c3c(cccn3)C(=O)C2=O)nc1

Synonyms:

• [1,10]Phenanthroline-5,6-Dione

1,10-Phenanthroline-5,6-dione

CAS: 27318-90-7

Formula: C₁₂H₆N₂O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 210.19

Ref: 3B-P1973

1,10-Phenanthroline-5,6-dione, 98%

CAS: 27318-90-7

1,10-Phenanthroline-5,6-dione is a Bifunctional quinone oxidant which, when used in conjunction with Zn2+ catalysts, is used to affect the aerobic oxidation of secondary amines to a variety of value added motifs, including indoles. This Thermo Scientific Chemicals brand product was originally part o

Formula: C₁₂H₆N₂O₂

Purity: 98%

Color and Shape: Off-white to yellow, Powder or crystals or crystalline powder

Molecular weight: 210.19

Ref: 02-H55747

1 10-PHENANTHROLINE-5 6-DIONE 97

CAS: 27318-90-7

Formula: C₁₂H₆N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 210.1882

Ref: IN-DA00BBP9

1,10-Phenanthroline-5,6-dione

CAS: 27318-90-7

1,10-Phenanthroline-5,6-dione

Formula: C₁₂H₆N₂O₂

Purity: 98%

Color and Shape: yellow solid

Molecular weight: 210.19g/mol

Ref: 54-OR16008

1,10-Phenanthroline-5,6-dione

CAS: 27318-90-7

Formula: C₁₂H₆N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 210.192

Ref: 10-F076956

1,10-Phenanthroline-5,6-dione

CAS: 27318-90-7

1,10-Phenanthroline-5,6-dione (PD) is a molecule that binds to the active site of many enzymes and inhibits their activity. PD has been shown to have antimicrobial activity against a number of bacteria and fungi. In vitro assays have shown that PD is effective against tumor cells in carcinoma cell lines. In vivo studies have also shown that PD can inhibit the growth of tumors in mice by inhibiting DNA synthesis. It has been found that PD competes with the cofactor NADH for binding to the enzyme dihydrofolate reductase, which is required for DNA synthesis. This inhibition leads to an increased amount of hydrogen peroxide, which reacts with iron ions in the enzyme ferritin, converting it into ferric hydroxide. The redox potentials of this reaction are reversed when NAD+ is added to the reaction mixture, leading to regeneration of NAD+ and allowing DNA synthesis to resume.
PD can be synthes

Formula: C₁₂H₆N₂O₂

Purity: Min. 95%

Molecular weight: 210.19 g/mol

Ref: 3D-FP60900