CAS 2745108-35-2

Formula: C17H15F3N2O4

InChI: InChI=1S/C17H15F3N2O4/c1-9(23)12-7-13(15(26-2)8-14(12)24)22-16(25)21-11-5-3-4-10(6-11)17(18,19)20/h3-8,24H,1-2H3,(H2,21,22,25)

InChI key: GHJDMUOTXYVBEB-UHFFFAOYSA-N

SMILES: CC(=O)C1=CC(=C(C=C1O)OC)NC(=O)NC2=CC=CC(=C2)C(F)(F)F

TOPK-p38/JNK-IN-1

CAS: 2745108-35-2

TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO

Formula: C₁₇H₁₅F₃N₂O₄

Color and Shape: Solid

Molecular weight: 368.31

Ref: TM-T61440