CAS 27532-96-3

Glycine tert-butyl ester hydrochloride

Description:

Glycine tert-butyl ester hydrochloride is a chemical compound that serves as an amino acid derivative and is often utilized in organic synthesis and pharmaceutical applications. It is characterized by its structure, which includes a glycine moiety linked to a tert-butyl ester group, along with a hydrochloride salt form that enhances its solubility in water. This compound typically appears as a white to off-white crystalline solid. It is known for its stability under standard conditions and is soluble in polar solvents, making it useful in various chemical reactions, particularly in peptide synthesis. Glycine tert-butyl ester hydrochloride can act as a protecting group for amino acids, allowing for selective reactions without interfering with other functional groups. Additionally, it may exhibit low toxicity, but standard safety precautions should be observed when handling it in a laboratory setting. Overall, its unique properties make it a valuable intermediate in the synthesis of more complex organic molecules.

Formula: C₆H₁₃NO₂·ClH

InChI: InChI=1S/C6H13NO2.ClH/c1-6(2,3)9-5(8)4-7;/h4,7H2,1-3H3;1H

InChI key: InChIKey=OSWULUXZFOQIRU-UHFFFAOYSA-N

SMILES: O(C(C)(C)C)C(CN)=O.Cl

Synonyms:

• 1,1-Dimethylethyl glycinate hydrochloride
• 2-(tert-Butoxy)-2-oxoethan-1-aminium chloride
• 2-Aminoacetic acid tert-butyl ester hydrochloride
• 2-Tert-Butoxy-2-Oxoethanaminium
• GLYCIN-tert-butyl ester hydrochloride
• GLYCINE T-butyl ester HCL
• Glycine tert butyl ester hydrochloride
• Glycine tert-butyl ester HCl
• Glycine tert-butyl ester monohydrochloride
• Glycine, 1,1-dimethylethyl ester, hydrochloride
• Glycine, 1,1-dimethylethyl ester, hydrochloride (1:1)
• H-Gly-OtBu.HCl
• H-Gly-OtBu・HCl
• Tert-Butyl Glycinate Hydrochloride
• tert-Butyl 2-aminoacetate hydrochloride

Glycine tert-Butyl Ester Hydrochloride

CAS: 27532-96-3

Formula: C₆H₁₃NO₂·HCl

Purity: >98.0%(T)(N)

Color and Shape: White powder to crystal

Molecular weight: 167.63

Ref: 3B-G0254

Glycine tert-butyl ester hydrochloride, 99%

CAS: 27532-96-3

Glycine t-butyl ester hydrochloride is a substituted Glycine used as parakeratosis inhibitor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar produc

Formula: C₆H₁₄NO₂

Purity: 99%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder or lumps

Molecular weight: 132.18

Ref: 02-L17116

H-Gly-OtBu · HCl

CAS: 27532-96-3

Bachem ID: 4002258.

Formula: C₆H₁₃NO₂·HCl

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 167.64

Ref: 01-4002258

Glycine tert-butyl ester hydrochloride

CAS: 27532-96-3

Formula: C₆H₁₄ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 167.6339

Ref: IN-DA0034Z3

Glycine tert-butyl ester hydrochloride

CAS: 27532-96-3

Glycine tert-butyl ester hydrochloride

Formula: C₆H₁₃NO₂·ClH

Purity: 98%

Color and Shape: white crystalline solid

Molecular weight: 167.63g/mol

Ref: 54-OR315773

Glycine tert-butyl ester hydrochloride

CAS: 27532-96-3

Formula: C₆H₁₃NO₂·HCl

Purity: ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 167.64

Ref: 7W-GM6763

H-Gly-OtBu.HCl

CAS: 27532-96-3

M03023 - H-Gly-OtBu.HCl

Formula: C₆H₁₄ClNO₂

Purity: 98%

Color and Shape: Solid, White solid

Molecular weight: 167.63

Ref: 10-M03023

Glycine t-butyl ester hydrochloride

CAS: 27532-96-3

Glycine t-butyl ester hydrochloride is a glycine prodrug that is converted to the neurotransmitter, cinchonidine, by carboxylesterase. It has been shown to be effective in resistant cancer cells and has good bioavailability in humans. Glycine t-butyl ester hydrochloride is synthesized from glycine and butyric acid with sodium carbonate as a catalyst and then reacted with anhydrous hydrogen chloride to form the final product. This synthesis requires an asymmetric reaction solution, which can be achieved by using a chiral reactant such as potassium carbonate or magnesium chloride. The dehydration of the ester group can be performed by heating in vacuum at 120°C for 2 hours.

Formula: C₆H₁₄ClNO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 167.63 g/mol

Ref: 3D-FG23689

Glycine t-Butyl Ester Hydrochloride

Controlled Product

CAS: 27532-96-3

Applications A substituted Glycine (G615990) used as parakeratosis inhibitor and external composition for skin.
References Pucci, B., et al.: Eur. Polymer J., 26, 731 (1990),

Formula: C₆H₁₃NO₂·ClH

Color and Shape: Neat

Molecular weight: 167.63

Ref: TR-G625175