CAS 2754408-94-9

N-(2-chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide

Description:

N-(2-chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide is a complex organic compound characterized by its unique structural features, including a sulfonamide group, multiple halogen substituents, and a quinazoline moiety. The presence of chlorine and fluorine atoms contributes to its potential biological activity and lipophilicity, which may enhance its interaction with biological targets. The azetidine ring adds to the compound's rigidity and may influence its pharmacokinetic properties. This compound is likely to exhibit specific reactivity due to the functional groups present, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Its intricate structure suggests potential applications in treating various diseases, possibly through mechanisms involving inhibition of specific enzymes or receptors. However, detailed studies on its biological activity, toxicity, and pharmacological profile would be necessary to fully understand its potential uses and safety.

Formula: C₁₈H₁₅Cl₂F₂N₅O₃S

Synonyms:

• N-(2-chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide
• N-[2-Chloro-3-[(5-chloro-3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-fluorophenyl]-3-fluoro-1-azetidinesulfonamide
• PF07799933
• Claturafenib

Claturafenib

CAS: 2754408-94-9

N-(2-Chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide

Formula: C₁₈H₁₅Cl₂F₂N₅O₃S

Purity: 95%

Molecular weight: 490.31

Ref: IN-DG02685472

N-(2-Chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide

CAS: 2754408-94-9

N-(2-Chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide

Formula: C₁₈H₁₅Cl₂F₂N₅O₃S

Purity: 95%

Molecular weight: 490.32

Ref: 54-PC1007078

Claturafenib

CAS: 2754408-94-9

Claturafenib is a brain-permeable, selective, all-mutant BRAF inhibitor.PF-07799933 has shown antitumor activity, used in combination with MEK inhibitors.

Formula: C₁₈H₁₅Cl₂F₂N₅O₃S

Purity: 98.68% - 99.85%

Color and Shape: Solid

Molecular weight: 490.31

Ref: TM-T201081