CAS 2761424-76-2

Formula: C23H18N4O2

InChI: InChI=1S/C23H18N4O2/c1-27-21(23(28)26-17-9-11-18(29-2)12-10-17)14-19-20(24-15-25-22(19)27)13-8-16-6-4-3-5-7-16/h3-7,9-12,14-15H,1-2H3,(H,26,28)

InChI key: OIYWWKBIBPZHKJ-UHFFFAOYSA-N

SMILES: CN1C(=CC2=C(N=CN=C21)C#CC3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)OC

mGluR5 antagonist-1

CAS: 2761424-76-2

mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].

Formula: C₂₃H₁₈N₄O₂

Color and Shape: Solid

Molecular weight: 382.41

Ref: TM-T81801