CAS 2765218-57-1

3-Isoxazolecarboxamide, N-[3-[4-[3-[3-(3-butyn-1-yl)-3H-diazirin-3-yl]-1-oxopropyl]-1-piperazinyl]propyl]-5-phenyl-

Formula: C₂₅H₃₀N₆O₃

InChI: InChI=1S/C25H30N6O3/c1-2-3-11-25(28-29-25)12-10-23(32)31-17-15-30(16-18-31)14-7-13-26-24(33)21-19-22(34-27-21)20-8-5-4-6-9-20/h1,4-6,8-9,19H,3,7,10-18H2,(H,26,33)

InChI key: VNBDOMPEKLAOMN-UHFFFAOYSA-N

SMILES: C#CCCC1(N=N1)CCC(=O)N2CCN(CC2)CCCNC(=O)C3=NOC(=C3)C4=CC=CC=C4

Synonyms:

• 3-Isoxazolecarboxamide, N-[3-[4-[3-[3-(3-butyn-1-yl)-3H-diazirin-3-yl]-1-oxopropyl]-1-piperazinyl]propyl]-5-phenyl-

PY-PAP

CAS: 2765218-57-1

PY-PAP is a photoactivatable affinity probe, derived from PY-60. It retains its cellular function of activating YAP transcription. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through UV crosslinking and click reactions. PY-PAP played a crucial role in identifying ANXA2 as a specific target of PY-60.

Formula: C₂₅H₃₀N₆O₃

Color and Shape: Solid

Molecular weight: 462.54

Ref: TM-T211351