CAS 2765823-81-0

NA

Formula: C₂₃H₂₁NO₂S

InChI: InChI=1S/C23H21NO2S/c1-2-16-6-5-9-20(12-16)27-22-13-17(10-11-21(22)25)23(26)24-14-18-7-3-4-8-19(18)15-24/h3-13,25H,2,14-15H2,1H3

InChI key: DXJOUWXZUXYSRX-UHFFFAOYSA-N

SMILES: CCC1=CC(=CC=C1)SC2=C(C=CC(=C2)C(=O)N3CC4=CC=CC=C4C3)O

Synonyms:

• [Synonyms]

HSP90-IN-28

CAS: 2765823-81-0

HSP90-IN-28 (compound 12 h) is a potent and selective Hsp90 inhibitor, with an IC50 of 0.46 μM for Hsp90α. It demonstrates approximately 48 times more selectivity for Hsp90α compared to Hsp90β (IC50 = 22.28 μM).

Formula: C₂₃H₂₁NO₂S

Molecular weight: 375.49

Ref: TM-T214858